{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:27:06Z","timestamp":1792549626059,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T00:00:00Z","timestamp":1496793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Amplitude\u2010integrated electroencephalogram (<jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content>) is widely used in neonates to detect electrical seizure and predict outcome following hypoxic ischaemic encephalopathy and other encephalopathy. Because accurate interpretation is important for clinical decision\u2010making and family counselling, inter\u2010observer reliability is a major concern. We aimed to evaluate inter\u2010observer reliability in the interpretation of <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content> tracings in a neonatal intensive care unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three neonatal intensive care unit clinicians with different levels of experience in reading <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content> independently reviewed and scored <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content> traces using standardised criteria, categories and interpretation rules. Inter\u2010observer reliability was evaluated using weighted Cohen's \u03ba and intra\u2010class correlation coefficients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 131 tracings from 120 neonates were reviewed by the neontalogist, 128 (97.7%) by the clinical nurse specialist, 73 (55.7%) by the nurse educator and 70 (53.4%) by all three clinicians. The majority (88 of 120, 73.3%) were term infants (mean <jats:styled-content style=\"fixed-case\">gestational age<\/jats:styled-content> 38 weeks, standard deviation 3.2). Average duration of recording was 27\u2009h (standard deviation 19.1, range 1\u2013105\u2009h). Inter\u2010observer reliability varied across categories and observers \u2013 from very good to excellent for the main background activity (intra\u2010class correlation coefficients 0.93\u20130.98); good to very good for seizures; and moderate to very good for sleep\u2013wake cycle and quality of recording (weighted \u03bas\u2019 0.71\u20130.85, 0.50\u20130.75, 0.46\u20130.81, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>While certain <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content> features appear challenging to inter\u2010observer reliability, our findings suggest that with training and consensus guidelines, levels of reliability needed to enhance clinical and prognostic usefulness of <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content> are achievable across clinicians with different levels of experience in reading <jats:styled-content style=\"fixed-case\">aEEG<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13589","type":"journal-article","created":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T06:58:54Z","timestamp":1496818734000},"page":"1007-1012","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Inter\u2010observer reliability in reading amplitude\u2010integrated electroencephalogram in the newborn intensive care unit"],"prefix":"10.1111","volume":"53","author":[{"given":"Bhavesh","family":"Mehta","sequence":"first","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaye","family":"Spence","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Laing","sequence":"additional","affiliation":[{"name":"School of Social Sciences and Psychology Western Sydney University  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073807306258"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2006.06.007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1294"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.086314"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318211c19e"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.4.506"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.11.005"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.6.1263"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/neo.7-2-e76"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.03.004"},{"key":"e_1_2_8_12_1","first-page":"19","volume-title":"Clinical Epidemiology: A Basic Science for Clinical Medicine","author":"Haynes RB","year":"1991"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnp.0000220094.60482.b5"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.1.e61"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.4135\/9781849209250","volume-title":"Health Science Research: A Handbook of Quantitative Methods","author":"Peat JK","year":"2002"},{"key":"e_1_2_8_16_1","unstructured":"NicholsDP.Choosing an Intraclass Correlation Coefficient. 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