{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:43:34Z","timestamp":1791999814042,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,9,3]],"date-time":"2017-09-03T00:00:00Z","timestamp":1504396800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1085775"],"award-info":[{"award-number":["1085775"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Large for gestational age (<jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>) babies have increased risks for short\u2010term outcomes such as shoulder dystocia, neonatal hypoglycaemia and longer hospital stay. Little is known of long\u2010term health, development and educational outcomes of <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> babies. The aim of this study was to determine the long\u2010term health, mortality, development and educational outcomes for infants born <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> at term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based record linkage study of live singletons born at term (37\u201341 weeks of gestation) in New South Wales, Australia, from 2001 to 2006.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study compared 49\u2009439 <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> (&gt;90th percentile for birthweight, gestational age and sex) and 400\u2009418 appropriate size for gestational age (<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>; 10th\u201390th percentile) infants. <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> infants had increased risk of birth and neonatal outcomes and hospitalisations, for brachial plexus injury after the neonatal period, and for all causes from 1 to 5 years of age. There were no differences in mortality up to 5 years of age or hospitalisations for type 1 diabetes in childhood. <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> infants had lower rates of developmental vulnerability (in kindergarten) and showed a significant trend (\u03c7<jats:sup>2<\/jats:sup> for trend &lt;0.0001) to fewer low scores and more high scores in reading and numeracy (in Year 3) compared with <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>. After adjusting for potential confounders, only the relative risk for higher reading scores was statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> infants show positive long\u2010term health, development and educational outcomes. Concerns for <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> infants still remain in the perinatal period as a result of birth trauma; however, these complications usually do not persist in postnatal and early childhood.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.13593","type":"journal-article","created":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T02:25:31Z","timestamp":1504491931000},"page":"876-881","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Long\u2010term outcomes for large for gestational age infants born at term"],"prefix":"10.1111","volume":"53","author":[{"given":"Amina Z","family":"Khambalia","sequence":"first","affiliation":[{"name":"Clinical and Population Perinatal Health Research Kolling Institute, Northern Sydney Local Health District  Sydney New South Wales Australia"},{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles S","family":"Algert","sequence":"additional","affiliation":[{"name":"Clinical and Population Perinatal Health Research Kolling Institute, Northern Sydney Local Health District  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer R","family":"Bowen","sequence":"additional","affiliation":[{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Neonatology Royal North Shore Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J","family":"Collie","sequence":"additional","affiliation":[{"name":"School of Education University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine L","family":"Roberts","sequence":"additional","affiliation":[{"name":"Clinical and Population Perinatal Health Research Kolling Institute, Northern Sydney Local Health District  Sydney New South Wales Australia"},{"name":"Sydney Medical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2012.01412.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70435-6"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200410000-00006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2009.02878.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2009.tb02420.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2002.128029"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-11-818"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443610400007828"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyr094"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.130.6.989"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207450802325843"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2390"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.11331"},{"key":"e_1_2_9_15_1","first-page":"372","article-title":"Neurodevelopmental consequences of being born SGA","volume":"2","author":"Wassenaer A","year":"2005","journal-title":"Pediatr. 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