{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:48:33Z","timestamp":1787507313801,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T00:00:00Z","timestamp":1499472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      Left vocal cord paralysis (\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      ) is variably reported post ligation of patent ductus arteriosus (\n                      <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>\n                      ). Our objective was to determine the incidence of\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      and identify predictive factors and associated morbidities in preterm infants post\n                      <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>\n                      ligation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This is a retrospective cohort study of infants less than\u200929 weeks gestational age from 2006 to 2014 who underwent\n                      <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>\n                      ligation. Infants with laryngeal symptoms underwent flexible fibreoptic nasopharyngolaryngoscopy to evaluate vocal cord function. We compared short\u2010 and long\u2010term morbidities among infants with and without symptomatic\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 35 infants underwent\n                      <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>\n                      ligation in the study period, of which 11 infants (31%) developed symptomatic\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      . Dysphonia was the presenting symptom in all neonates with\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      and stridor was present in 46% (5\/11) of them. The median (interquartile range) gestation (25 weeks (24\u201327) vs. 25 weeks (23\u201328)), birthweight (810\u2009g (550\u20131180) vs. 825\u2009g (550\u20131220)) and age at surgery (19\u2009days (9\u201327) vs. 20 (5\u201369)) were similar in infants with and without\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      , respectively. Infants with\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      took significantly longer to reach suck feeds (128 vs. 90 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009&lt;0.001), stayed longer in hospital (119 vs. 95 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01) and were more likely to go home on oxygen (73 vs. 27%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.024). Neurodevelopmental outcomes were similar in the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      was noted in 31% of infants post\n                      <jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>\n                      ligation and was associated with prolonged hospital stay, a longer time to reach suck feeds and a need for home oxygen. No predictive factors for development of\n                      <jats:styled-content style=\"fixed-case\">LVCP<\/jats:styled-content>\n                      were identified.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.13632","type":"journal-article","created":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T02:56:35Z","timestamp":1499482595000},"page":"1192-1198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Unilateral vocal cord paralysis after surgical closure of a patent ductus arteriosus in extremely preterm infants"],"prefix":"10.1111","volume":"53","author":[{"given":"Pramod","family":"Pharande","sequence":"first","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sathiyapriya","family":"Karthigeyan","sequence":"additional","affiliation":[{"name":"Centre for Newborn Care Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Walker","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne","family":"D'Cruz","sequence":"additional","affiliation":[{"name":"Centre for Newborn Care Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Badawi","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Luig","sequence":"additional","affiliation":[{"name":"Centre for Newborn Care Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Winlaw","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himanshu","family":"Popat","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Care Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.1_Spec_No.58"},{"key":"e_1_2_8_3_1","first-page":"CD003951","article-title":"Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants","author":"Malviya MN","year":"2013","journal-title":"Cochrane Database Syst. 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