{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:17:59Z","timestamp":1790651879803,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,28]],"date-time":"2017-08-28T00:00:00Z","timestamp":1503878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2018,1]]},"abstract":"\n Aim<\/jats:title>\n \n To determine the range of cerebral blood flow velocities (\n CBFVs<\/jats:styled-content>\n ) and Doppler indices of cerebrovascular resistance in normal\u2010term neonates as a baseline for a study of hypoxic\u2010ischaemic encephalopathy.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The\n CBFV<\/jats:styled-content>\n s, resistive index (\n RI<\/jats:styled-content>\n ) and pulsatility index (\n PI<\/jats:styled-content>\n ) were measured in the anterior and middle cerebral arteries (\n ACA<\/jats:styled-content>\n and\n MCA<\/jats:styled-content>\n ) of 38 normal neonates.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The mean peak systolic, end diastolic and time\u2010averaged velocities (\n PSV<\/jats:styled-content>\n ,\n EDV<\/jats:styled-content>\n and\n TAV<\/jats:styled-content>\n ) were 36.3 \u00b1 6.6, 12.4 \u00b1 3.9 and 22.0 \u00b1 4.0 cm\/s (\n ACA<\/jats:styled-content>\n ) and 41.4 \u00b1 13.2, 13.0 \u00b1 5.5 and 25.8 \u00b1 7.9 cm\/s (\n MCA<\/jats:styled-content>\n ), respectively. All\n CBFV<\/jats:styled-content>\n s in the\n ACA<\/jats:styled-content>\n correlated with gestation; only\n EDV<\/jats:styled-content>\n was correlated to post\u2010natal age. The\n RI<\/jats:styled-content>\n in the\n ACA<\/jats:styled-content>\n (0.67 \u00b1 0.06) and\n MCA<\/jats:styled-content>\n (0.68 \u00b1 0.07) were correlated (\n r<\/jats:italic>\n = 0.72,\n P<\/jats:italic>\n < 0.001);\n RI<\/jats:styled-content>\n correlated to post\u2010natal age. Two infants with RI < 0.55 were both fed within 25 mins of the study; RI correlated with post\u2010prandial time (dichotomous, pivot 25 min). The mean\n PI<\/jats:styled-content>\n was 1.11 \u00b1 0.18 (\n ACA<\/jats:styled-content>\n ) and 1.17 \u00b1 0.23 (\n MCA<\/jats:styled-content>\n ). Correlations were observed with post\u2010natal age and post\u2010prandial time (dichotomous). The average angle of insonation was greater in the\n ACA<\/jats:styled-content>\n than in the\n MCA<\/jats:styled-content>\n (median of 5\u00b0 vs. 18\u00b0).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Results corresponded with previous published studies. No correlation was observed between Doppler indices and gestation as component velocities all increase with advancing gestation. Less variation and smaller standard deviation of CBFV's was associated with a smaller angle of insonation. Low\n RI<\/jats:styled-content>\n s (<0.55), without a pathological cause, warrants further study.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jpc.13663","type":"journal-article","created":{"date-parts":[[2017,8,28]],"date-time":"2017-08-28T04:56:42Z","timestamp":1503896202000},"page":"61-68","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Cerebral blood flow velocities and cerebrovascular resistance in normal\u2010term neonates in the first 72 hours"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9908-2610","authenticated-orcid":false,"given":"Danielle E","family":"Forster","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit Mercy Hospital for Women Melbourne Victoria Australia"},{"name":"Department of Medical Imaging Mercy Hospital for Women Melbourne Victoria Australia"},{"name":"Department of Electrical and Electronic Engineering University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Koumoundouros","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit Mercy Hospital for Women Melbourne Victoria Australia"},{"name":"Department of Electrical and Electronic Engineering University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Saxton","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Mercy Hospital for Women Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Fedai","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Mercy Hospital for Women Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Holberton","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit Mercy Hospital for Women Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199206000-00022"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-21320-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1542\/peds.70.1.147a","article-title":"Cerebral blood flow velocity in the human newborn: The value of its determination","volume":"70","author":"Volpe JJ","year":"1982","journal-title":"Pediatrics"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56724-7"},{"key":"e_1_2_8_6_1","volume-title":"Velocimetrie Ultrasonore Doppler","author":"Pourcelot L","year":"1974"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80735-0"},{"key":"e_1_2_8_8_1","volume-title":"Neurology of the Newborn","author":"Volpe JJ","year":"2008"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-001-1150-z"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.73.2.F75"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80373-X"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2010.12.003"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(90)90028-H"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.4.425"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80700-5"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437385.88715.4a"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.11331"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162201002870"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2009000300017"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(83)80055-2"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.171.1.2648468"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002470000286"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-39842012000500006"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2014.11"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.6.606"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02387890"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(83)80054-0"},{"key":"e_1_2_8_28_1","first-page":"737","article-title":"Cerebral blood flow velocity in normal, full\u2010term newborns is not related to ductal closure","volume":"146","author":"Batton DG","year":"1992","journal-title":"Am. 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