{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:39:51Z","timestamp":1792723191528,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,14]],"date-time":"2018-02-14T00:00:00Z","timestamp":1518566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study sought to determine whether scabies infection is associated with acute rheumatic fever (ARF) or chronic rheumatic heart disease (CRHD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cohort study was undertaken using health records of children aged 3\u201312 years attending an oral health service for the first time. Subjects were then linked to hospital diagnoses of scabies and ARF or CRHD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 213 957 children free of rheumatic heart disease at baseline were available for analysis. During a mean follow\u2010up time of 5.1 years, 440 children were diagnosed with ARF or CRHD in hospital records. Children diagnosed with scabies during follow\u2010up were 23 times more likely to develop ARF or CRHD, compared with children who had no scabies diagnosis. After adjustment for confounders in a Cox model, the association reduced but remained strong (adjusted hazard ratio: 8.98; 95% confidence interval: 6.33\u201320.2). In an analysis restricted to children hospitalised at least once during follow\u2010up, the adjusted hazard ratio for the same comparison was 3.43 (95% confidence interval: 1.85\u20136.37).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A recent diagnosis of scabies from hospital records is strongly associated with a subsequent diagnosis of ARF. Further investigation of the role that scabies infestation may play in the aetiology of ARF is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.13851","type":"journal-article","created":{"date-parts":[[2018,2,14]],"date-time":"2018-02-14T05:22:48Z","timestamp":1518585768000},"page":"625-632","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Scabies is strongly associated with acute rheumatic fever in a cohort study of Auckland children"],"prefix":"10.1111","volume":"54","author":[{"given":"Simon","family":"Thornley","sequence":"first","affiliation":[{"name":"Communicable Diseases and Disease Investigation Auckland Regional Public Health Service  Auckland New Zealand"},{"name":"Section of Epidemiology and Biostatistics University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Marshall","sequence":"additional","affiliation":[{"name":"Section of Epidemiology and Biostatistics University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Jarrett","sequence":"additional","affiliation":[{"name":"Department of Medicine Counties Manukau District Health Board, Middlemore Hospital  Auckland New Zealand"},{"name":"Department of Medicine, Faculty of Medicine and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Sundborn","sequence":"additional","affiliation":[{"name":"Section of Epidemiology and Biostatistics University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Communicable Diseases and Disease Investigation Auckland Regional Public Health Service  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Schofield","sequence":"additional","affiliation":[{"name":"Human Potential Centre, Millennium Institute Auckland University of Technology  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2008.01384.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S12977"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/506938"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2002.00850.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(04)00975-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03798.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12133"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2016-208219"},{"key":"e_1_2_9_10_1","volume-title":"NZDep2006 Index of Deprivation User's Manual","author":"Salmond C","year":"2007"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2098"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4172\/2155-6180.1000e111"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-19425-7"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2016.03.011"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005726"},{"key":"e_1_2_9_16_1","first-page":"59","article-title":"Rheumatic fever diagnosis, management, and secondary prevention: A New Zealand guideline","volume":"121","author":"Atatoa\u2010Carr P","year":"2008","journal-title":"N. 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