{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:18:53Z","timestamp":1779110333206,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T00:00:00Z","timestamp":1546387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Q fever is a zoonotic disease caused by the bacterium <jats:italic>Coxiella burnetii<\/jats:italic> and is associated with significant morbidity and mortality in both adults and children. Australia is the only country that has produced and registered a Q fever vaccine for human use, but this vaccine is licenced only for people aged over 15\u2009years as data and experience in children are limited. This review describes the experience of Q fever vaccination of known paediatric cases in Australia to date.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients aged younger than 15 years who received the Q fever vaccination had data abstracted from medical records after consent was obtained from the relevant guardians. Data on risk factors for Q fever, skin testing procedure, dose of vaccination, adverse effects and follow\u2010up assessment were obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve children were identified as having received the Q fever vaccination. Vaccination was feasible, with empirical weight\u2010based dose adjustment performed for younger children. There were no significant adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Q fever vaccine may be safe in children and should be considered in children who are at significant risk of Q fever infection. Safe vaccine protocols with proven efficacy will allow children of all ages to be protected. Prospective studies of vaccination in children are indicated. Expanding available Q fever registries to include children would allow outcomes to be systematically followed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.14364","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T04:34:40Z","timestamp":1546490080000},"page":"1099-1102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Q fever vaccination of children in Australia: Limited experience to date"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1223-3699","authenticated-orcid":false,"given":"Mark","family":"Armstrong","sequence":"first","affiliation":[{"name":"Infectious Diseases Unit Royal Brisbane and Women's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh","family":"Francis","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Royal Darwin Hospital  Darwin Northern Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny","family":"Robson","sequence":"additional","affiliation":[{"name":"Department of Microbiology Sullivan and Nicolaides Pathology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Graves","sequence":"additional","affiliation":[{"name":"Australian Rickettsial Reference Laboratory Geelong Hospital  Geelong Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Mills","sequence":"additional","affiliation":[{"name":"The Travel Doctor Travel Medicine Alliance Clinics Australia  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Health Pathology New South Wales John Hunter Hospital  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare","family":"Nourse","sequence":"additional","affiliation":[{"name":"Infection Management and Prevention Service Lady Cilento Children's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(02)00440-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200011000-00019"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68266-4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001211"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000970"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00045-16"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12051"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/16.2.282"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-6405.2010.00478.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1225-y"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.10-0268"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1071\/NB07057"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2011.00892.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.02.007"},{"key":"e_1_2_8_16_1","unstructured":"Department of Health Australian Government.National Notifiable Diseases Surveillance System; 2017. Available from:http:\/\/www9.health.gov.au\/cda\/source\/cda-index.cfm[accessed 10 April 2017]."},{"key":"e_1_2_8_17_1","unstructured":"Queensland Health Queensland Government.Q Fever: Queensland Health Guidelines for Public Health Units; 2010. Available from:https:\/\/www.health.qld.gov.au\/cdcg\/index\/qfever.asp[accessed 8 November 2016]."},{"key":"e_1_2_8_18_1","volume-title":"The Australian Immunisation Handbook","author":"Department of Health, Australian Government","year":"2016"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2007.tb00853.x"},{"key":"e_1_2_8_20_1","volume-title":"A Guide to Q Fever and Q Fever Vaccination","author":"Commonwealth Serum Laboratories Biotherapies","year":"2009"},{"key":"e_1_2_8_21_1","first-page":"41","article-title":"Enhanced Q fever risk exposure surveillance may permit better informed vaccination policy","volume":"33","author":"Irwin M","year":"2009","journal-title":"Commun. Dis. Intell. Q. 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