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However, as not all children with PO\u2010IBD will have poor outcome and the best management decisions involve weighing risks versus benefit and wishes of patient's and family, we review risk factors of IBD progression in children and summarise rapidly expanding treatment choices, potential drug\u2010related adverse events and risk minimisation strategies, ending with new treatment paradigms focusing on long\u2010term goal of intestinal healing. For the purpose of this article, we have outlined the conventional approach, including medications currently licenced and available for use in Australia for paediatric IBD through the Pharmaceutical Benefit Scheme and briefly discuss other promising therapies that are shown to be effective in adults but are undergoing paediatric clinical trials.<\/jats:p>","DOI":"10.1111\/jpc.14652","type":"journal-article","created":{"date-parts":[[2019,10,15]],"date-time":"2019-10-15T11:24:30Z","timestamp":1571138670000},"page":"1677-1684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Management of inflammatory bowel disease in children: It is time for an individualised approach"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5925-4166","authenticated-orcid":false,"given":"Zubin","family":"Grover","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Perth Children's Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Alex","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Royal Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,15]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.05.006"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.079"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.081"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21152"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.10.006"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04857.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21559"},{"key":"e_1_2_4_9_1","first-page":"1386","article-title":"Predicting endoscopic Crohn's disease activity before and after induction therapy in children: A comprehensive assessment of PCDAI, CRP, and fecal calprotectin","volume":"21","author":"Grover Z","year":"2015","journal-title":"Inflamm. 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