{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:25:34Z","timestamp":1762374334960,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study compared the outcomes of patients with biliary atresia (BA) treated according to a standardised protocol with historical patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a single\u2010centred retrospective study of BA patients treated from 1980 to 2016. A standardised treatment protocol was established since 2008 regarding peri\u2010operative management. The outcomes being compared between the two groups (Groups I and II = before and after 2008, respectively) were jaundice clearance (JC), incidence of recurrent cholangitis, hospital admission and native liver survival (NLS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 128 patients were included (Group I = 100, Group II = 28). The overall median follow\u2010up period was 15.3\u2009years (I vs. II = 20.6\u2009years vs. 5.1\u2009years, respectively). There was no significant difference in the JC at the sixth month between the two groups (I vs. II = 60.0 vs. 82.1%, respectively, <jats:italic>P<\/jats:italic> = 0.07). The incidence of recurrent cholangitis was similar between the two groups (I vs. II = 39 vs. 35.7%, respectively, <jats:italic>P<\/jats:italic> = 0.45), but the median hospital admission episode per patient was non\u2010significantly higher in Group I (I vs. II = 4.2 vs. 2.7, respectively, <jats:italic>P<\/jats:italic> = 0.08). There was an improvement in the 1\u2010year NLS rate in Group II (I vs. II = 69.0 vs. 85.7%, respectively, <jats:italic>P<\/jats:italic> = 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The introduction of a standardised management protocol has improved the short\u2010term outcome of BA patients, with a better 1\u2010year NLS observed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.14698","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:35:13Z","timestamp":1605573313000},"page":"1774-1778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Standard management protocol to improve the short\u2010term outcome of biliary atresia"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2382-5681","authenticated-orcid":false,"given":"Patrick HY","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Surgery, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth KY","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Surgery, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul KH","family":"Tam","sequence":"additional","affiliation":[{"name":"Department of Surgery, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-008-2190-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-008-2200-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181e8e194"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-014-1024-z"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)03492-3"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(03)00499-8"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2003.12.014"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.12.054"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21219"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.05.051"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181633562"},{"key":"e_1_2_6_13_1","first-page":"473","article-title":"Biliary atresia: The Brazilian experience","volume":"86","author":"Carvalho E","year":"2010","journal-title":"J. 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