{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T06:52:51Z","timestamp":1777099971185,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to identify the incidence, risk factors and outcome associated with meconium aspiration syndrome (MAS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An observational study was conducted in 12 public hospitals in Nepal from 1 July 2017 to 29 August 2018. All babies born within the study period were included in the study. Babies who were diagnosed as MAS were designated as outcome. Data were analysed with bivariate analysis followed by multiple regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall incidence of MAS was 2.0 per 1000 livebirths. Babies born at post\u2010term gestation (adjusted odds ratio (AOR) = 2.41; 95% confidence interval (CI): 1.05\u20135.55), nulliparity (AOR = 2.26; 95% CI: 1.20\u20134.28), instrumental delivery (AOR = 4.79; 95% CI: 2.52\u20139.10) and caesarean delivery (AOR = 3.67; 95% CI: 2.29\u20135.89) were significantly associated with MAS. Babies with MAS had a 10\u2010fold risk for pre\u2010discharge mortality (odds ratio = 9.87; 95% CI: 5.81\u201316.76).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings in this study are consistent with that reported in other studies. MAS has a high risk of neonatal mortality. Thus, monitoring during pregnancy and labour is necessary for early identification of high\u2010risk conditions associated with MAS. Strengthening of newborn care services is essential to curtail mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.14703","type":"journal-article","created":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T12:33:25Z","timestamp":1577968405000},"page":"630-635","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Meconium aspiration syndrome: incidence, associated risk factors and outcome\u2010evidence from a multicentric study in low\u2010resource settings in Nepal"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3518-3236","authenticated-orcid":false,"given":"Prajwal","family":"Paudel","sequence":"first","affiliation":[{"name":"Ministry of Health and Population  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9965-181X","authenticated-orcid":false,"given":"Avinash K","family":"Sunny","sequence":"additional","affiliation":[{"name":"Research Division, Golden Community  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pragya G","family":"Poudel","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Tennessee  Knoxville United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4262-3543","authenticated-orcid":false,"given":"Rejina","family":"Gurung","sequence":"additional","affiliation":[{"name":"Research Division, Golden Community  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2512-1485","authenticated-orcid":false,"given":"Abhishek","family":"Gurung","sequence":"additional","affiliation":[{"name":"Research Division, Golden Community  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramchandra","family":"Bastola","sequence":"additional","affiliation":[{"name":"Ministry of Health and Population  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram N","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Ministry of Health and Population  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8614-1087","authenticated-orcid":false,"given":"Shyam S","family":"Budhathoki","sequence":"additional","affiliation":[{"name":"Research Division, Golden Community  Lalitpur Nepal"},{"name":"Department of Primary Care and Public Health School of Public Health, Imperial College London  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0541-4486","authenticated-orcid":false,"given":"K C","family":"Ashish","sequence":"additional","affiliation":[{"name":"International Maternal and Child Health, Department of Women's and Children's Health Uppsala University  Uppsala Sweden"},{"name":"Society of Public Health Physicians Nepal  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0065-3101(22)00677-6","article-title":"Meconium in health and disease","volume":"26","author":"Antonowiez I","year":"1979","journal-title":"Adv. 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