{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:04:15Z","timestamp":1764687855878,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the epidemiology and outcomes of gastroschisis in Tasmania.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of all pregnancies complicated by gastroschisis in Tasmania from 1996 to 2015 was undertaken (epidemiology cohort), and the presentation, surgical management and outcomes (surgery cohort) were reviewed for the period between September 1990 and July 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Gastroschisis was detected in 58 pregnancies during the 20\u2010year epidemiology cohort period, giving an incidence of 4.4 per 10\u2009000 live births for the 20\u2010year period. Two of the four stillbirths occurred after 36\u2009weeks' gestation. Of the 65 babies with gastroschisis treated at the Royal Hobart Hospital, 51 had a staged surgical repair (silo in 47, stoma formation in 4), and 14 had a primary closure. Staged repair was associated with a significantly longer duration of ventilation and stay in the neonatal intensive care unit. There were six post\u2010natal deaths, all born in the first epoch. Death was significantly associated with the condition of the intestine at delivery (<jats:italic>P<\/jats:italic> =\u20090.02). There were no deaths in babies with simple gastroschisis. Complex gastroschisis was significantly associated with longer duration of total parenteral nutrition (<jats:italic>P<\/jats:italic> =\u20090.0002) and longer stay in hospital (<jats:italic>P<\/jats:italic> =\u20090.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence of gastroschisis in Tasmania is similar to that reported in other Australian regions and has not increased over the 20\u2010year period of study. The high risk of stillbirth, and the significant association between mortality and the condition of the intestine at birth necessitates close fetal surveillance. Complex gastroschisis imposes a significant burden on hospital resources.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.14863","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T14:24:35Z","timestamp":1584714275000},"page":"1795-1798","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiology and outcomes of gastroschisis in Tasmania"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6298-5066","authenticated-orcid":false,"given":"Gopakumar","family":"Hariharan","sequence":"first","affiliation":[{"name":"Department of Neonatal and Paediatric Intensive Care Unit (NPICU) Royal Hobart Hospital  Hobart Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niall","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Royal Hobart Hospital  Hobart Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ee","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Royal Hobart Hospital  Hobart Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"De Paoli","sequence":"additional","affiliation":[{"name":"Department of Neonatal and Paediatric Intensive Care Unit (NPICU) Royal Hobart Hospital  Hobart Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80640-3"},{"key":"e_1_2_8_3_1","first-page":"A10","article-title":"Epidemiology of gastroschisis and exomphalos in Tasmania 1990\u20132005","volume":"45","author":"Walwyn T","year":"2009","journal-title":"J. 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