{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:37:41Z","timestamp":1747186661547,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T00:00:00Z","timestamp":1599868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Eosinophilic oesophagitis (EoE) is a rare, chronic, relapsing immune\/antigen\u2010mediated disease characterised by symptoms of oesophageal dysfunction, with a paucity of data among New Zealand (NZ) children. This 3\u2010year prospective study aimed to characterise EoE diagnosed nationally and to describe initial treatment strategies adopted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Information on new diagnoses of paediatric EoE was obtained via the New Zealand Paediatric Surveillance Unit, through monthly questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From February 2014 to January 2017, 73 new cases (74% male) of EoE were reported, including 74% NZ European, 10% Asian, 7% M\u0101ori, 5% Middle\u2010Eastern and 3% Pacific peoples. Median age of symptom onset was 4\u2009years; dysphagia (48%) was the most common, followed by vomiting\/regurgitation (40%), food impaction (19%) and epigastric pain (16%). A co\u2010morbid history of other allergic conditions was present in 62% of patients, and 41% had a first degree relative with atopy. Seventy\u2010nine percent of patients had abnormal endoscopic findings, most commonly linear furrows and white plaques; none had strictures. Median eosinophil count per high\u2010powered field was 40 and 50 in the mid and distal oesophagus, respectively. Fifty\u2010four percent of patients were initially managed with dietary manipulation alone (four required elemental feeds, five nasogastric tubes). Fifty\u2010four percent of patients were treated with swallowed corticosteroids and 7% with prednisone. One patient was also treated with a leukotriene receptor antagonist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This first prospective study on paediatric patients with EoE in NZ finds similar demographics and disease characteristics as in other populations despite our unique ethnic population. Long\u2010term prospective observational data should significantly improve our knowledge of this rare condition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.15183","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T21:15:56Z","timestamp":1613855756000},"page":"234-238","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Paediatric eosinophilic oesophagitis in New Zealand: A 3\u2010year prospective study"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7873-7385","authenticated-orcid":false,"given":"Amin J","family":"Roberts","sequence":"first","affiliation":[{"name":"Department of Paediatric Gastroenterology Starship Child Health, University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2290-7386","authenticated-orcid":false,"given":"Andrew S","family":"Day","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Department of Paediatric Allergy and Clinical Immunology Starship Child Health  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel","family":"Dickson","sequence":"additional","affiliation":[{"name":"New Zealand Paediatric Surveillance Unit University of Otago  Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jody","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Otago Christchurch  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Wellington","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology Starship Child Health, University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8860-2705","authenticated-orcid":false,"given":"Helen M","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology Starship Child Health, University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3182a80be1"},{"key":"e_1_2_7_3_1","first-page":"78","article-title":"Paediatric non\u2010IgE mediated food allergy: Guide for practitioners","volume":"129","author":"Preece K","year":"2016","journal-title":"N. 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