{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T03:19:09Z","timestamp":1785467949433,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T00:00:00Z","timestamp":1607385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>We diagnosed varicella zoster virus (VZV) meningitis in a healthy adolescent boy who presented without a rash or fever. We aim to compare VZV reactivation meningitis in children after primary VZV infection and VZV vaccination. We reviewed the literature up until June 2020 using Pubmed\/MEDLINE and EMBASE databases using \u2018varicella zoster\u2019, \u2018meningitis\u2019 and \u2018children\u2019 as keywords. Only English articles were included. Twenty\u2010five cases were included in this review. Children who had VZV reactivation meningitis after vaccination were younger (7\u2009\u00b1\u20093.4\u2009years vs. 11.9\u2009\u00b1\u20093.6\u2009years, <jats:italic>P<\/jats:italic> =\u20090.0038), had a shorter interval between first exposure to reactivation (5.6\u2009\u00b1\u20092.9\u2009years vs. 8.8\u2009\u00b1\u20093.2\u2009years, <jats:italic>P<\/jats:italic> =\u20090.018) and more likely to have a rash (100% vs. 55%, <jats:italic>P<\/jats:italic> =\u20090.04). VZV reactivation meningitis occurs after both primary VZV infection and VZV vaccination. The absence of exanthem, fever or meningism does not rule out VZV meningitis.<\/jats:p>","DOI":"10.1111\/jpc.15303","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T02:48:59Z","timestamp":1607568539000},"page":"19-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Primary varicella zoster infection compared to varicella vaccine reactivation associated meningitis in immunocompetent children"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8950-7398","authenticated-orcid":false,"given":"Vanessa","family":"Amaral","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Zhuo","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita Man\u2010ching","family":"Tsang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan Shui\u2010seng","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-39-72"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2008.10.023"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809336296"},{"key":"e_1_2_5_5_1","first-page":"53","article-title":"V1\u2010distributed herpes zoster and meningitis in a two\u2010year old","volume":"8","author":"Wang AS","year":"2015","journal-title":"J. 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