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Penicillin allergy labels (PALs) are important pieces of the medical history that guide physicians in selecting specific antibiotic classes for the treatment of infectious diseases. However, most children labelled as penicillin\u2010allergic do not have an IgE\u2010mediated (immediate) allergic reaction to penicillin or its derivatives. In the absence of confirmatory penicillin allergy testing or additional history, these children receive alternative, often broad\u2010spectrum and second\u2010line, antibiotics. Addressing unconfirmed PALs requires an understanding of how and why labels get added to the electronic medical record. This viewpoint highlights the knowledge gaps in paediatric outpatient penicillin allergy labelling and proposes an acronym (\u2018LABEL\u2019) that primary care providers and antimicrobial stewards can utilise when designing initiatives to address unconfirmed PALs in the community.<\/jats:p>","DOI":"10.1111\/jpc.15445","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T11:12:11Z","timestamp":1615893131000},"page":"607-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Unconfirmed penicillin allergy labels in the paediatric outpatient setting: A call for research and quality improvement initiatives"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5537-6350","authenticated-orcid":false,"given":"Margaret","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Section of Infectious Diseases Baylor College of Medicine  Houston Texas United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Anvari","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Immunology, Allergy, and Retrovirology Baylor College of Medicine  Houston Texas United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra","family":"Palazzi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Infectious Diseases Baylor College of Medicine  Houston Texas United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2019.1617132"},{"key":"e_1_2_3_3_1","first-page":"162","article-title":"Positive allergological tests may turn negative with no further exposure to the specific allergen: A long\u2010term, prospective, follow\u2010up study in patients allergic to penicillin","volume":"6","author":"Patriarca G","year":"1996","journal-title":"J. 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