{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:42:37Z","timestamp":1771476157395,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T00:00:00Z","timestamp":1626912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To report the outcome for infants with congenital diaphragmatic hernia (CDH) and identify clinical factors affecting outcome from a tertiary perinatal surgical campus where extracorporeal membrane oxygenation (ECMO) is available however rarely utilised.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of infants with CDH born in a co\u2010located perinatal neonatal intensive care unit (NICU) or retrieved into and managed at a surgical NICU: 2003\u20132018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and fifty\u2010nine infants with CDH were identified. One hundred and twenty were born in the co\u2010located hospital and 39 retrieved from outlying hospitals. Survival of all patients with CDH was 74.8%; The survival for all isolated left CDH was 89% and the survival of post\u2010surgery was 93%. Two patients went onto ECMO and both died.<\/jats:p><jats:p>Associated major congenital anomalies were seen in 13.2%. Low birthweight (&lt; 2500\u2009g), 5\u2010min Apgar &lt;5, antenatal diagnosis, right\u2010sided diaphragmatic hernia, herniation of the liver, associated major congenital anomalies, high oxygenation index (&gt;25) on day 1, inotrope use, inhaled nitric oxide and need for high\u2010frequency ventilation were associated with increased mortality on univariate analysis. Neurodevelopmental follow\u2010up was commenced in 2013. Forty\u2010three infants were discharged and developmental data were available for 36 at 4\u00a0months (83%) and 32 at 1\u00a0year (73%). Outcomes revealed normal motor scores and expressive language with mild delay in the receptive language at 1\u00a0year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the low use of ECMO, our centre's results reveal excellent survival and neurodevelopmental outcomes consistent with or better than international data.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.15659","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T17:58:47Z","timestamp":1626976727000},"page":"90-96","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Outcomes for infants with congenital diaphragmatic hernia: A single campus review with low extracorporeal membrane oxygenation utilisation"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8662-6458","authenticated-orcid":false,"given":"Yogesh","family":"Khachane","sequence":"first","affiliation":[{"name":"Grace Centre for Newborn Intensive Care The Children's Hospital at Westmead  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Halliday","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Intensive Care The Children's Hospital at Westmead  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Surgery The Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health, The Children's Hospital of Westmead Clinical School University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health, The Children's Hospital of Westmead Clinical School University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Neonatology Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Browning Carmo","sequence":"additional","affiliation":[{"name":"Grace Centre for Newborn Intensive Care The Children's Hospital at Westmead  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health, The Children's Hospital of Westmead Clinical School University of Sydney  Sydney New South Wales Australia"},{"name":"Neonatal and Paediatric Emergency Transport Service Sydney Children's Hospitals Network  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/sper.2000.21111"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.01.073"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2009.194"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.16000"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.12.008"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2011.03.002"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.09.060"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.09.010"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1393960"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.10.078"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx120"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001612"},{"key":"e_1_2_6_14_1","article-title":"Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants","volume":"3","author":"Mugford M","year":"2008","journal-title":"Cochrane Database Syst. 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