{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:54:09Z","timestamp":1783464849275,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Establishing the underlying cause in a child with chronic suppurative lung disease (CSLD) allows for targeted treatment and screening for associated complications. One cause of CSLD is primary ciliary dyskinesia (PCD). Testing for PCD requires specialist expertise which is not widely available. Computed tomography (CT) scans are commonly performed when assessing CSLD. Identifying PCD\u2010specific signs on CT would help clinicians in deciding when to refer for specialist testing. One potential PCD\u2010specific sign we have observed is fissure adjacent partial lobe atelectasis (FAPLA). We aimed to assess if FAPLA is commonly found in CT of PCD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010eight CT scans from 42 adult and child PCD patients were analysed. The presence and distribution of FAPLA were noted, and its association to sputum culture and other signs commonly seen in CSLD (bronchiectasis, bronchial wall thickening, air trapping and mucus plugging).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>FAPLA was found in 13 of 40 participants in their earliest CT scan. The prevalence of FAPLA was similar in children and adults. FAPLA involved the right middle lobe in all 13 cases and was systematically associated with \u22651 other structural change. There was no association between FAPLA and bacterial isolation from sputum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>FAPLA was found in 32.5% PCD scans, without difference between children and adults in terms of frequency. Future work will determine if it is a PCD\u2010specific sign by assessing whether it is also found in other CSLD processes and analysing more scans from children with PCD to determine how early this sign develops.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.15818","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T07:39:47Z","timestamp":1637134787000},"page":"683-686","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Fissure adjacent partial lobe atelectasis in primary ciliary dyskinesia"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3259-1648","authenticated-orcid":false,"given":"Loraine","family":"Fabri","sequence":"first","affiliation":[{"name":"Infection and Immunity Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Brussels  Anderlecht Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6000-3180","authenticated-orcid":false,"given":"Shivanthan","family":"Shanthikumar","sequence":"additional","affiliation":[{"name":"Infection and Immunity Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Department of Respiratory and Sleep Medicine The Royal Children's Hospital Melbourne  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn","family":"Tadd","sequence":"additional","affiliation":[{"name":"Medical Workforce Unit Eastern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Concord Hospital  Sydney New South Wales Australia"},{"name":"School of Medicine The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Schultz","sequence":"additional","affiliation":[{"name":"Wal\u2010yan Respiratory Research Centre Telethon Kids Institute, The University of Western Australia  Perth Western Australia Australia"},{"name":"Department of Respiratory Medicine Perth Children's Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Robinson","sequence":"additional","affiliation":[{"name":"Infection and Immunity Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Department of Respiratory and Sleep Medicine The Royal Children's Hospital Melbourne  Melbourne Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201511-748OC"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01551-2015"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201904-347OT"},{"key":"e_1_2_8_5_1","first-page":"95","article-title":"Chest imaging in the study of primary ciliary dyskinesia in children","volume":"14","author":"P\u00e9rez MLC","year":"2019","journal-title":"Neumol. 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