{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T10:52:41Z","timestamp":1750157561597,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Explore the prevalence of childhood anaphylaxis and clinical presentation of anaphylaxis in children across two regional emergency departments over a 7\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective audit of all children (0\u201318\u2009years) presenting to emergency from 1 January 2010 to 31 December 2016 with anaphylaxis, defined by Australasian Society of Clinical Immunology and Allergy definitions and doctor diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven hundred and twenty\u2010four patients were identified with allergic diagnosis, 60% were diagnosed with non\u2010anaphylaxis allergic reactions or unspecified urticaria and 40% with anaphylaxis (<jats:italic>n<\/jats:italic>\u00a0=\u2009286). Annual prevalence of anaphylaxis remained stable over the study period (<jats:italic>M<\/jats:italic>\u00a0=\u200930.9\/10 000 cases, range: 20.8\u201348.3\/10 000). Gender distribution was equal, median age was 9.48\u2009years (interquartile range\u00a0=\u00a04\u201315). Most (71%) arrived by private transport. 23% had a prior history of anaphylaxis. Food triggers (44%) were the most common cause of anaphylaxis. Insect bites\/stings triggers occurred in 21%. Patients were promptly assessed (average wait time\u00a0=\u00a013\u2009min), 16% received prior adrenaline injections. Adrenaline was administered in 26% and 20% were admitted to hospital. On discharge, 29% had a follow\u2010up plan, 9% received an allergy clinic referral, 6% anaphylaxis action plan, 26% adrenaline autoinjector prescriptions and allergy testing performed in 6%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found a relatively low prevalence of overall childhood anaphylaxis in a regional area. The two most common causes of anaphylaxis in this population (food and bites\/stings) recorded increased prevalence providing an opportunity for further study. Significant gaps in evidence\u2010based care of anaphylaxis were noted, demonstrating the need for improved recognition and treatment guideline implementation in regional areas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16006","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T13:10:54Z","timestamp":1651669854000},"page":"1407-1413","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Emergency department childhood anaphylaxis presentations in regional\/remote Australia"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0290-0355","authenticated-orcid":false,"given":"Heinrich C","family":"Weber","sequence":"first","affiliation":[{"name":"Tasmanian Health Service  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7077-929X","authenticated-orcid":false,"given":"Gaylene L","family":"Bassett","sequence":"additional","affiliation":[{"name":"Tasmanian Health Service  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura K","family":"Hollingsworth","sequence":"additional","affiliation":[{"name":"Tasmanian School of Medicine, Rural Clinical School, University of Tasmanian  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent WS","family":"Gan","sequence":"additional","affiliation":[{"name":"Tasmanian School of Medicine, Rural Clinical School, University of Tasmanian  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Rose","sequence":"additional","affiliation":[{"name":"Tasmanian School of Medicine, Rural Clinical School, University of Tasmanian  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Lim","sequence":"additional","affiliation":[{"name":"Tasmanian Health Service  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5782-9141","authenticated-orcid":false,"given":"Sarah J","family":"Prior","sequence":"additional","affiliation":[{"name":"Tasmanian School of Medicine, University of Tasmania  Burnie Tasmania Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000305"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.10.021"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.10.049"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.05.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.50604"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2000.00444.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2010.03573.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.33151\/ajp.12.3.235"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.33151\/ajp.13.1.298"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.09.018"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000000864"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.13483"},{"key":"e_1_2_8_14_1","unstructured":"Guidelines A. 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