{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T10:20:19Z","timestamp":1785838819586,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T00:00:00Z","timestamp":1657584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to assess the effect of iron deficiency on parent\u2010reported changes in quality of life (QOL) among children receiving an adenotonsillectomy for paediatric obstructive sleep apnoea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective review study that recruited children under 16\u2009years of age undergoing an adenotonsillectomy, adenoidectomy, or tonsillectomy for clinically diagnosed paediatric OSA between June 2020 and January 2021 inclusive, in Western Australia. The main outcome measures for this study were changes in QOL by age group and iron status, defined by an absolute change of more than 3 points on OSA\u201018 survey domains.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>About 249 participants had iron studies performed on perioperative blood samples drawn at operation and completed both pre\u2010operative and post\u2010operative OSA\u201018 QOL questionnaires at initial consultation and 8\u201312\u2009weeks post\u2010surgery, respectively. 41.8% were iron deficient, 53.8% were borderline iron deficient and 4.4% had normal iron levels. Following surgery, a decrease was observed for all OSA\u201018 score domains in post\u2010operation scores compared to pre\u2010operation scores in both iron\u2010deficient and borderline iron\u2010deficient cohorts. \u2018Daytime Problems\u2019 in the &lt;2\u2009years group, within the iron\u2010deficient cohort, was the only domain that found to be non\u2010superior (i.e. \u2018not better\u2019) following surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Following adenotonsillectomy, patients with paediatric OSA reported significant improvements in QOL regardless of their iron status. Those undergoing an adenotonsillectomy for paediatric OSA had a high prevalence of iron deficiency at operation, especially those under 6\u2009years of age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16115","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T13:34:32Z","timestamp":1657632872000},"page":"1816-1823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effect of iron deficiency on quality of life outcomes after surgery for obstructive sleep apnoea"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0481-0855","authenticated-orcid":false,"given":"Zachary","family":"Reynolds","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health Sciences University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Hibbert","sequence":"additional","affiliation":[{"name":"Perth ENT Centre  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Stevenson","sequence":"additional","affiliation":[{"name":"Telethon Kids Institute, University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyan","family":"Vijayasekaran","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences University of Western Australia  Perth Western Australia Australia"},{"name":"Perth ENT Centre  Perth Western Australia Australia"},{"name":"St John of God Hospital  Subiaco Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,12]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"CD011165","article-title":"Tonsillectomy or adenotonsillectomy versus non\u2010surgical management for obstructive sleep\u2010disordered breathing in children","volume":"2015","author":"Venekamp RP","year":"2015","journal-title":"Cochrane Database Syst. 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Sydney: ACSQHC 2015."},{"key":"e_1_2_7_10_1","unstructured":"National Blood Authority Australia. In:Paediatric and Neonatal Iron Deficiency Anaemia Guide: Guideline for Australian Health Providers. Issue ISBN 978\u20100\u20109944061\u20108\u20107. 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