{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:08:55Z","timestamp":1792084135493,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,5]],"date-time":"2022-11-05T00:00:00Z","timestamp":1667606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Reticulocyte haemoglobin (Ret\u2010He) is a useful marker in the assessment of iron stores in adult and paediatric patients. It is currently not utilised in Pathology Queensland. The objective of this study is to verify Ret\u2010He in our Pathology Queensland laboratory and assess the clinical utility in the assessment of iron deficiency (ID) and iron deficiency anaemia (IDA) in paediatric patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Samples from patients aged &lt;18\u2009years sent to the Pathology Queensland laboratory that had paired full blood count and iron studies were included in this study. A minimum of 120 samples were required for verification of testing requirements and a minimum of 30 samples per age range were required for confirmation of published age\u2010related reference intervals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Published Ret\u2010He reference intervals were confirmed for stated age ranges in normal (non\u2010ID) patients. Ret\u2010He below the reference range for age demonstrated a good correlation with ID and IDA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ret\u2010He is a useful marker in the assessment of ID and IDA in a paediatric population. It is not affected by acute or chronic inflammation. Ret\u2010He is sensitive and specific (86% and 92%) for the diagnosis of ID.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16265","type":"journal-article","created":{"date-parts":[[2022,11,5]],"date-time":"2022-11-05T09:59:50Z","timestamp":1667642390000},"page":"153-158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical utility of reticulocyte haemoglobin in the assessment of iron deficiency and iron deficiency anaemia in the paediatric population"],"prefix":"10.1111","volume":"59","author":[{"given":"Malaika","family":"Perchard","sequence":"first","affiliation":[{"name":"Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Barbaro","sequence":"additional","affiliation":[{"name":"Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Rane","sequence":"additional","affiliation":[{"name":"Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Norman","sequence":"additional","affiliation":[{"name":"Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,5]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.Iron Deficiency Anaemia Assessment Prevention and Control: A Guide for Programme Managers. The Organization;Geneva Switzerland:World Health Organisation;2001. 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