{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T06:50:40Z","timestamp":1767163840057,"version":"build-2238731810"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To determine the quality of paediatric guidelines relevant to diagnosis of three of the most common conditions in primary care: fever, gastroenteritis and constipation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We undertook a meta\u2010epidemiological study of paediatric guidelines for fever, gastroenteritis and gastroenteritis. We systematically searched MEDLINE, Embase, Trip Database, Guidelines International Network, the National Guideline Clearinghouse and WHO from February 2011 to September 2022 for guidelines from high\u2010income settings containing diagnostic recommendations. We assessed the quality of guideline reporting for included guidelines using the AGREE II tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 16 guidelines: fever (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097); constipation (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094) and gastroenteritis (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095). The overall quality across the three conditions was graded moderate (median AGREE II score 4.5\/7, range 2.5\u20136.5) with constipation guidelines rated the highest (median 6\/7), and fever rated the lowest (median 3.8\/7). Major methodological weaknesses included consideration of guideline applicability. Half of the guidelines did not report involving parent representatives, and 56% did not adequately declare or address their competing interests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Substantial variations exist in the quality of paediatric guidelines related to the diagnosis of primary care presentations. Better quality guidance is needed for general practitioners to improve diagnosis for children in primary care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.16454","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T10:07:40Z","timestamp":1687169260000},"page":"1053-1060","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The quality of diagnostic guidelines for children in primary care: A meta\u2010epidemiological study"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7008-8763","authenticated-orcid":false,"given":"Elizabeth T","family":"Thomas","sequence":"first","affiliation":[{"name":"Centre for Evidence\u2010Based Medicine, Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0717-2246","authenticated-orcid":false,"given":"Sarah T","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Neurology Gold Coast University Hospital  Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2418-2091","authenticated-orcid":false,"given":"Rafael","family":"Perera","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6253-1312","authenticated-orcid":false,"given":"Peter J","family":"Gill","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford United Kingdom"},{"name":"Department of Paediatrics, Faculty of Medicine University of Toronto  Toronto Ontario Canada"},{"name":"Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9724-8816","authenticated-orcid":false,"given":"Susan","family":"Moloney","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Gold Coast University Hospital  Gold Coast Queensland Australia"},{"name":"School of Medicine Griffith University  Gold Coast Queensland Australia"},{"name":"Faculty of Health Sciences and Medicine Bond University  Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1009-1992","authenticated-orcid":false,"given":"Carl","family":"Heneghan","sequence":"additional","affiliation":[{"name":"Centre for Evidence\u2010Based Medicine, Nuffield Department of Primary Care Health Sciences University of Oxford  Oxford United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14739879.2016.1266697"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2020-321045"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp20X709289"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000144100.29945.5e"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-019-1455-x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-020-1911-y"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0224681"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2018.06.013"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-2686"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-02693-1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/ebmed-2017-110713"},{"key":"e_1_2_8_13_1","unstructured":"NICE.Fever in under 5s: Assessment and initial management NICE guideline [NG143]. NICE Guidelines Online. 2019."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-052228"},{"key":"e_1_2_8_15_1","unstructured":"The Royal Children's Hospital Melbourne.Febrile child; 2022. Available from:https:\/\/www.rch.org.au\/clinicalguide\/guideline_index\/Febrile_child\/[accessed 4 October 2022]."},{"key":"e_1_2_8_16_1","unstructured":"Government of South Australia Department of Health and Wellbeing.Fever in Children aged 1\u20132 months. 2022. Available from:https:\/\/www.sahealth.sa.gov.au\/wps\/wcm\/connect\/public+content\/sa+health+internet\/resources\/policies\/fever+in+children+aged+1\u20102+months+\u2010+sa+paediatric+clinical+guideline#:~:text=Non%2Dtoxic%20infants%20aged%201 Children%20aged%201%2D2%20months[accessed 4 October 2022]."},{"key":"e_1_2_8_17_1","unstructured":"NHG working group BergerMY BerghuisICA et al.Children with fever. 2016. Available from:https:\/\/richtlijnen.nhg.org\/standaarden\/kinderen\u2010met\u2010koorts#volledige\u2010tekst\u2010belangrijkste\u2010wijzigingen[accessed 4 September 2022]."},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2016.04.028"},{"key":"e_1_2_8_19_1","unstructured":"Cincinnati Children's.Evidence\u2010Based Care Guideline for Management of Infants 0 to 60\u2009days with Fever of Unknown Source Guideline 10. 2019. Available from:https:\/\/www.cincinnatichildrens.org\/\u2010\/media\/cincinnati%20childrens\/home\/service\/j\/anderson\u2010center\/evidence\u2010based\u2010care\/recommendations\/default\/fever%20of%20unknown%20source%20guideline%2010.pdf?la=en[accessed 4 September 2022]."},{"key":"e_1_2_8_20_1","unstructured":"NICE.Constipation in children and young people: Diagnosis and management. Clinical Guideline 2010."},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000266"},{"key":"e_1_2_8_22_1","unstructured":"Federatie Medisch Specialisten.Constipation in children aged 0 to 18\u2009years. 2015. Available from:https:\/\/richtlijnendatabase.nl\/richtlijn\/obstipatie_bij_kinderen_van_0_tot_18_jaar\/obstipatie_\u2010_startpagina.html[accessed 4 October 2022]."},{"key":"e_1_2_8_23_1","unstructured":"Government of South Australia Department for Health and Wellbeing.Constipation in Children. 2022. Available from:https:\/\/www.sahealth.sa.gov.au\/wps\/wcm\/connect\/public+content\/sa+health+internet\/resources\/policies\/constipation+in+children+\u2010+sa+paediatric+clinical+guideline[accessed 4 October 2022]."},{"key":"e_1_2_8_24_1","unstructured":"NICE Guidelines.Diarrhoea and vomiting caused by gastroenteritis in under 5s: Diagnosis and management. 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Pract."},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-4-54"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12875-017-0650-0"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.31128\/AJGP-08-19-5028"}],"updated-by":[{"DOI":"10.1111\/jpc.16505","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000}}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.16454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T05:15:48Z","timestamp":1695186948000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.16454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,19]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/jpc.16454"],"URL":"https:\/\/doi.org\/10.1111\/jpc.16454","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,19]]},"assertion":[{"value":"2023-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}