{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:09:37Z","timestamp":1784740177400,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the effect of resuscitation with bubble CPAP (bCPAP) versus T\u2010piece device at birth on early clinical parameters and hospital outcomes in infants born &lt;32\u2009weeks gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a single\u2010centre pre\u2010 and post\u2010implementation study comparing outcomes in two epochs. In epoch 1 (1 July 2013\u201331 December 2014), infants were managed with non\u2010humidified gas using Neopuff\u00ae T\u2010piece devices to support breathing after birth. In epoch 2 (1 March 2020\u201331 December 2021), routine application of bCPAP with humidified gas was introduced at birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred fifty\u2010seven patients were included (176 epoch 1, 181 epoch 2). The mean gestational age was 28\u2009\u00b1\u20092\u2009weeks. The demographics of the two epochs were comparable. There were significant improvements in outcomes of infants in epoch 2 with less infants intubated at delivery (16% vs. 4%, <jats:italic>P<\/jats:italic>\u2009\u2264\u20090.001), improved 5\u2009min Apgar (7 vs. 8, <jats:italic>P<\/jats:italic>\u2009\u2264\u20090.001), reduced need for ventilation (21% vs. 8.8%, <jats:italic>P<\/jats:italic>\u2009\u2264\u20090.001), duration of ventilation in the first 72\u2009h (9.6 vs. 4.6\u2009h) and mortality (10.8% vs. 1.7%, <jats:italic>P<\/jats:italic>\u2009\u2264\u20090.001). There was, increased incidence of chronic lung disease (30% vs. 55%, <jats:italic>P<\/jats:italic>\u2009=\u20090.02) but no increase in infants discharged on oxygen (3.8% vs. 5%, <jats:italic>P<\/jats:italic>\u2009=\u20090.25). Similar findings were observed in a subgroup of infants born &lt;25\u2009weeks' gestation with no increase in the incidence of CLD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Introducing application of bCPAP from the first breaths in infants &lt;32\u2009weeks' gestation was associated with better short\u2010term outcomes and mortality, albeit with increased incidence of CLD. The subgroup of infants born &lt;25\u2009weeks' gestation showed similar change in outcomes, with no increase in CLD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16608","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T11:34:55Z","timestamp":1720006495000},"page":"428-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Provision of bubble <scp>continuous positive airway pressure<\/scp> for the stabilisation of extremely and very preterm infants after birth: A single\u2010centre experience"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2277-4547","authenticated-orcid":false,"given":"Nele","family":"Legge","sequence":"first","affiliation":[{"name":"Liverpool Hospital  Liverpool New South Wales Australia"},{"name":"University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8181-9648","authenticated-orcid":false,"given":"Dominic","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"University of Sydney  Sydney New South Wales Australia"},{"name":"Children's Hospital Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himanshu","family":"Popat","sequence":"additional","affiliation":[{"name":"University of Sydney  Sydney New South Wales Australia"},{"name":"Children's Hospital Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1880"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f5980"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2019.08.043"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2020-320198"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.174003"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.115"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2012.17"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000071008"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80854-2"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2021.1497"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.1660"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2014.04.017"},{"key":"e_1_2_7_14_1","volume-title":"Report of the Australian and New Zealand Neonatal Network 2019","author":"Chow SSW","year":"2021"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000499361"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.21892"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.03.004"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7210904"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5984305"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.10.231"},{"key":"e_1_2_7_21_1","first-page":"69","volume":"2016","author":"Subramaniam P","year":"2016","journal-title":"Cochrane Database of Syst. 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