{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T20:08:51Z","timestamp":1784318931116,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2024,10]]},"abstract":"Aim<\/jats:title>Urticaria multiforme is an uncommon presentation of acute urticaria. It most commonly affects children and most often occurs secondary to an underlying viral infection. We performed a retrospective review of a cohort of Asian children with urticaria multiforme and reviewed the literature on the condition.<\/jats:p><\/jats:sec>Methods<\/jats:title>We retrospectively reviewed the clinical notes of children and adolescents less than 16\u2009years of age, diagnosed with urticaria multiforme at our tertiary paediatric hospital between January 2017 and December 2022. Data collected and analysed included age, gender, initial diagnosis, antecedent symptoms, recent immunisations and medications, results of diagnostic tests, treatment and outcome.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 20 children were identified, with median age of diagnosis of 1.9\u2009years, with most patients (79%) 7\u2009years of age or younger. Viral infections were the commonest triggers. The most common referring diagnoses were erythema multiforme and Stevens\u2013Johnson syndrome. Common antecedent or concomitant symptoms were fever and upper respiratory symptoms. Blood investigations were generally unremarkable except for mildly increased white cell counts and other markers of infection. Outcomes were good in all patients, with resolution of symptoms within 6\u2009weeks without sequelae.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Urticaria multiforme is an uncommon presentation of acute urticaria. Despite its striking appearance, it is generally a benign, self\u2010limiting condition. Extensive investigations are usually not required and management is largely supportive.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16634","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T08:05:08Z","timestamp":1722931508000},"page":"538-543","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Urticaria multiforme in Asian children"],"prefix":"10.1111","volume":"60","author":[{"given":"Sheau Y","family":"Kan","sequence":"first","affiliation":[{"name":"Department of Dermatology KK Women's & Children's Hospital Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark JA","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Dermatology KK Women's & Children's Hospital Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette WY","family":"Wee","sequence":"additional","affiliation":[{"name":"Department of Dermatology KK Women's & Children's Hospital Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1997.tb00246.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1553"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-241011"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2019.09.005"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2021.9159"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12103"},{"key":"e_1_2_5_8_1","first-page":"427","article-title":"Urticaria multiforme in a 2\u2010year\u2010old girl","volume":"32","author":"Gavin M","year":"2019","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01311.x"},{"key":"e_1_2_5_10_1","first-page":"34","article-title":"Urticaria multiforme","volume":"6","author":"Emer JJ","year":"2013","journal-title":"J. Clin. Aesthet. 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