{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:20:01Z","timestamp":1788456001691,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Intraventricular haemorrhage (IVH) and periventricular leukomalacia (PVL) in preterm infants are associated with an increased risk of long\u2010term neurodevelopmental impairments (NDI) and cerebral palsy (CP). However, little is known about their impact on early neurodevelopmental outcomes despite increasing evidence highlighting the feasibility and importance of early NDI\/CP diagnosis. We aimed to determine the early neurodevelopmental outcomes of preterm infants with IVH and PVL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective single\u2010centre cohort study of preterm infants born at &lt;29\u2009weeks gestation or &lt;1000\u2009g birth weight who attended an Early Neurodevelopment Clinic at 3 to 4\u2009months of corrected age. Primary outcomes of early NDI and CP\/high\u2010risk CP diagnoses based on Prechtl's General Movements Assessment and the Hammersmith Infant Neurological Examination were compared between infants without IVH and infants with mild IVH (grades I\u2010II), severe IVH (grades III\u2010IV), and severe brain injury (SBI; severe IVH or cystic PVL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 313 infants, 52.1% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009163), 41.2% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009129), 6.7% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200921) and 8.6% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200927) had no IVH, mild IVH, severe IVH and SBI, respectively. The adjusted odds of early CP\/high\u2010risk CP diagnosis were significantly higher in infants with severe IVH (aOR 6.07, 95% CI 1.50\u201324.50) and SBI (aOR 15.28, 95% CI 3.70\u201363), but not in those with mild IVH (aOR 1.24, 95% CI 0.49\u20133.10). However, the adjusted odds of any early NDI were similar across groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Preterm infants with severe IVH and SBI are at increased risk of early CP\/high\u2010risk of CP diagnosis at 3 to 4\u2009months of corrected age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.16654","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T03:09:05Z","timestamp":1724641745000},"page":"669-674","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Early neurodevelopmental outcomes of preterm infants with intraventricular haemorrhage and periventricular leukomalacia"],"prefix":"10.1111","volume":"60","author":[{"given":"Nicole SC","family":"Ng","sequence":"first","affiliation":[{"name":"Department of Paediatrics Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Razak","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Monash University  Melbourne Victoria Australia"},{"name":"Monash Newborn Monash Children's Hospital  Melbourne Victoria Australia"},{"name":"The Ritchie Centre Hudson Institute of Medical Research  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preethi","family":"Chandrasekharan","sequence":"additional","affiliation":[{"name":"Monash Newborn Monash Children's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenda","family":"McLean","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Monash Children's Hospital  Melbourne Victoria 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Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9664-4182","authenticated-orcid":false,"given":"Atul","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Monash University  Melbourne Victoria Australia"},{"name":"Monash Newborn Monash Children's Hospital  Melbourne Victoria Australia"},{"name":"The Ritchie Centre Hudson Institute of Medical Research  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,26]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Report of the Australian and New Zealand Neonatal Network 2021","author":"Chow 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