{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T15:51:11Z","timestamp":1751385071263,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the incidence and presenting features of type 1 diabetes mellitus and diabetic ketoacidosis in a paediatric population serviced by a regional health service in Queensland, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients less than 16\u2009years old diagnosed with type 1 diabetes mellitus between 01 January 2015 and 31 December 2021 were included in this retrospective, observational study. The electronic medical records of each patient were reviewed to collect data on demographics, presentation and ongoing diabetes care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010four paediatric patients were diagnosed with type 1 diabetes mellitus during the study period, giving an incidence of 25 cases per 100\u2009000 person years. Half the patients presented with diabetic ketoacidosis, with 14 (22% of the total cohort) presenting in severe diabetic ketoacidosis. There was no significant increase in the incidence of type 1 diabetes mellitus or proportion of patients with diabetic ketoacidosis across the years of the study. Patients that had a delayed diagnosis had an increased likelihood of presenting with severe diabetic ketoacidosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Incidence of type 1 diabetes mellitus in the paediatric population in this regional centre in Queensland, Australia, is similar to national data. High proportions of patients presenting with diabetic ketoacidosis and severe diabetic ketoacidosis were identified in the study population, with delayed diagnosis, a risk factor for severe diabetic ketoacidosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jpc.16673","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T04:23:49Z","timestamp":1726806229000},"page":"730-736","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence and presenting features of paediatric type 1 diabetes mellitus and diabetic ketoacidosis in a regional Australian health service"],"prefix":"10.1111","volume":"60","author":[{"given":"Shaun","family":"Cousen","sequence":"first","affiliation":[{"name":"Paediatrics Department Mackay Base Hospital  Mackay Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7054-1492","authenticated-orcid":false,"given":"Matthew","family":"Hiskens","sequence":"additional","affiliation":[{"name":"Mackay Institute of Research and Innovation Mackay Base Hospital  Mackay Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Signal","sequence":"additional","affiliation":[{"name":"Paediatric Diabetes and Endocrinology Department Queensland Children's Hospital  Brisbane Queensland Australia"},{"name":"Paediatric Endocrinology Department University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkat","family":"Vangaveti","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry James Cook University  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopakumar","family":"Hariharan","sequence":"additional","affiliation":[{"name":"Paediatrics Department Mackay Base Hospital  Mackay Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"volume-title":"Incidence of Insulin\u2010Treated Diabetes in Australia 2020","year":"2022","author":"Australian Institute of Health and Welfare","key":"e_1_2_6_2_1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-018-4763-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-013-3090-y"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-015-3709-2"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12773"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajr.12805"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0205"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27996"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.14417"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15081"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-020-05152-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep10358"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-010-1704-1"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13205"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13327"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12666"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12891"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1742-6723.14320"},{"key":"e_1_2_6_21_1","first-page":"263","article-title":"Diabetic ketoacidosis (DKA) at diabetes diagnosis in children (0\u201318\u2009years) in Ontario, Canada: A population\u2010based retrospective cohort study of health administrative data","volume":"3","author":"Mian O","year":"2018","journal-title":"Int. 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