{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T12:02:08Z","timestamp":1773748928247,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004895","name":"European Social Fund Plus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Study the influence of a variety of perinatal factors on the presence of metabolic syndrome and its parameters in prepubertal age, considering socio\u2010demographic factors, sex, Tanner stage and weight status of the preadolescent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data collected from the cross\u2010sectional Healthy Growth Study (2007) in students from four prefectures of Greece and their families. Cardiometabolic risk factors (waist circumference, blood pressure and blood indices) and perinatal data (from parents and health records) were collected. Single and a multiple logistic regression performed to assess the associations with cardiometabolic risk in preadolescence. Dependent variables included waist circumference, blood glucose, HDL\u2010C, TG, blood pressure and metabolic syndrome presence, while independent variables encompassed perinatal factors categorised as pre\u2010pregnancy, during and post\u2010pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>2666 pre\u2010adolescents (mean age 11.2\u2009year) participated in the study. After adjustment for parental educational level, family income, sex, Tanner stage and weight category, maternal pre\u2010pregnancy weight was positively associated with high waist circumference (OR, 95% CI 1.02 (1.00\u20131.04)), low HDL\u2010C levels (OR, 95% CI 1.01 (1.00\u20131.03)) and metabolic syndrome (OR, 95% CI 1.02 (1.00\u20131.05)). Timing of solid foods' introduction was positively associated with high waist circumference (OR, 95% CI 1.09 (1.01\u20131.08)), gestational age with high glucose levels (OR, 95% CI 1.12 (1.04\u20131.19)), smoking (OR, 95% CI 1.07 (1.00\u20131.14)) and alcohol consumption (OR, 95% CI 2.35 (1.05\u20135.27)) during the first trimester of breastfeeding with high glucose levels and low HDL\u2010C levels, respectively. Number of previous miscarriages was positively associated with low HDL\u2010C levels (OR, 95% CI 1.28 (1.04\u20131.57)). Gestational age was negatively associated with high waist circumference (OR, 95% CI 0.87 (0.80\u20130.95)) and iron supplementation in the third pregnancy trimester negatively association with high TG levels (OR, 95% CI 0.34 (0.12\u20130.91)).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal weight, perinatal behaviours, infant feeding and miscarriages influence pre\u2010pubertal cardiometabolic health, independent of sociodemographics, sex, Tanner stage and weight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.16791","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T05:33:56Z","timestamp":1738733636000},"page":"701-713","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Perinatal Factors and Family Sociodemographic Characteristics With Cardiometabolic Health in Pre\u2010Adolescence: Cross\u2010Sectional Results From Healthy Growth Study"],"prefix":"10.1111","volume":"61","author":[{"given":"Ioanna","family":"Nakaki","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3102-4684","authenticated-orcid":false,"given":"Aikaterini M.","family":"Kontochristopoulou","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Costas","family":"Anastasiou","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Moschonis","sequence":"additional","affiliation":[{"name":"Department of Food, Nutrition and Dietetics, School of Allied Health, Human Services and Sport La Trobe University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anela","family":"Halilagic","sequence":"additional","affiliation":[{"name":"Department of Food, Nutrition and Dietetics, School of Allied Health, Human Services and Sport La Trobe University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingting","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Food, Nutrition and Dietetics, School of Allied Health, Human Services and Sport La Trobe University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Karaglani","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannis","family":"Manios","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Harokopio University  Athens Greece"},{"name":"Institute of Agri\u2010Food and Life Sciences Hellenic Mediterranean University Research Centre  Heraklion 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