{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:08:42Z","timestamp":1772993322618,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Minimally\/less invasive surfactant therapy\/administration (MIST\/LISA) is increasingly used for surfactant delivery in preterm infants with respiratory distress syndrome, aiming to reduce complications associated with invasive methods. Despite its growing adoption, variations in clinical practice remain.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate MIST\/LISA use in Portuguese neonatal intensive care units (NICUs) and identify variations in practice.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A national, anonymous questionnaire was distributed to neonatologists. The survey explored surfactant administration techniques, experience with MIST\/LISA, device preferences, premedication strategies and protocols. Responses were analysed descriptively.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Fifty\u2010two responses were collected. Most respondents reported using MIST\/LISA (87%), preferring it over INSURE or standard intubation. Practices varied widely in pre\u2010intervention drug use and catheter choice.\n Surfcath<\/jats:italic>\n was the most used device (71%). Only one\u2010third consistently used pre\u2010sedation.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n MIST\/LISA is widely implemented in Portuguese NICUs, but substantial variability exists. Standardised guidelines are needed to optimise clinical outcomes and reduce practice heterogeneity.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jpc.70247","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:54:08Z","timestamp":1764309248000},"page":"181-185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["MIST<\/scp>\n \/\n LISA<\/scp>\n in Portugal: National Survey of Clinical Practice"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2819-9130","authenticated-orcid":false,"given":"S\u00edlvia Duarte","family":"Costa","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Unidade Local de Sa\u00fade de Matosinhos Hospital Pedro Hispano Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4995-6886","authenticated-orcid":false,"given":"Sofia Silva","family":"Faria","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Unidade Local de Sa\u00fade de Matosinhos Hospital Pedro Hispano Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udia","family":"Ferraz","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Unidade Local de Sa\u00fade de Matosinhos Hospital Pedro Hispano Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Unidade Local de Sa\u00fade de Matosinhos Hospital Pedro Hispano Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"issue":"3","key":"e_1_2_10_2_1","first-page":"1","article-title":"European Consensus Guidelines on the Management of Respiratory Distress Syndrome \u2013 2022 Update","volume":"120","author":"Sweet D. 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A.","year":"2021","journal-title":"Journal of the American Medical Association"}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.70247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jpc.70247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.70247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T14:35:18Z","timestamp":1772980518000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.70247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/jpc.70247"],"URL":"https:\/\/doi.org\/10.1111\/jpc.70247","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]},"assertion":[{"value":"2025-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}