{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:47:35Z","timestamp":1791607655153,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016182","name":"Universidade Federal de Mato Grosso do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016182","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["404346\/2023\u20105"],"award-info":[{"award-number":["404346\/2023\u20105"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>STORCH refers to a group of congenital infections (syphilis, toxoplasmosis, rubella, cytomegalovirus and herpes) that can impact the central nervous system. As clinical signs may not appear until several months or years after birth, the early detection of risk in STORCH\u2010exposed infants has been challenging, and the use of sensitive tools in this population is understudied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare STORCH\u2010exposed infants with non\u2010exposed controls using the Hammersmith Infant Neurological Examination (HINE) at 3\u2009months of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is an observational cohort study. A total of 60 infants were included and equally allocated into two groups: an exposed group, whose mothers had a clinically confirmed diagnosis of a classic STORCH infection during pregnancy, and a non\u2010exposed control group, whose mothers did not present STORCH infections during gestation. At 3\u2009months of age (13.83\u2009\u00b1\u20091.09\u2009weeks post\u2010term), infants were assessed using the HINE. Group comparisons were performed for the global score, subscores across the five scorable domains (cranial nerve function, posture, spontaneous movements, tone and reflexes and reactions), number of asymmetries and risk of cerebral palsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The exposed group showed lower global scores and lower subscores in most HINE domains compared to controls, along with a higher frequency of asymmetries and an increased proportion of infants classified as at high risk for cerebral palsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Infants prenatally exposed to STORCH infections showed an increased risk of impairment based on the HINE when compared to controls. Potential neurological limitations were detectable in the exposed group at 3\u2009months of age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.70273","type":"journal-article","created":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T04:54:12Z","timestamp":1767243252000},"page":"374-380","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hammersmith Infant Neurological Examination at 3\u2009Months in Infants at Risk for Congenital Infections: A Cohort Study"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3251-5634","authenticated-orcid":false,"given":"Karen Cristine Oliveira","family":"de Azambuja","sequence":"first","affiliation":[{"name":"Graduate Program in Movement Sciences Federal University of Mato Grosso do Sul  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4075-9256","authenticated-orcid":false,"given":"Amanda","family":"de Arguelho Oliveira Arguelho","sequence":"additional","affiliation":[{"name":"Graduate Program in Movement Sciences Federal University of Mato Grosso do Sul  Campo Grande Mato Grosso do Sul Brazil"},{"name":"Graduate Program in Health and Development Federal University of Mato Grosso do Sul  Campo Grande Mato Grosso do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1001-840X","authenticated-orcid":false,"given":"Meyene Duque","family":"Weber","sequence":"additional","affiliation":[{"name":"Graduate Program in Movement Sciences Federal University of Mato Grosso do Sul  Campo Grande Mato Grosso do Sul Brazil"},{"name":"Health Institute Federal University of Mato Grosso do Sul  Campo Grande Mato Grosso do Sul 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