{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:57:44Z","timestamp":1781153864491,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder characterized by prominent nutritional and gastrointestinal challenges. This study aimed to evaluate the nutritional status, gastrointestinal symptoms and biochemical deficiencies in children with DMD, with a particular focus on the clinical utility of supplementary anthropometric indicators such as mid\u2010upper arm circumference Z\u2010score (MUAC\u2010Z) and triceps skinfold thickness Z\u2010score (TSF\u2010Z). This cross\u2010sectional study included 65 genetically confirmed DMD patients aged 5\u201318\u2009years. Anthropometric data (BMI\u2010SDS, MUAC\u2010Z, TSF\u2010Z), gastrointestinal complaints, serum vitamin D levels and clinical features were analysed. ROC curve analysis was conducted to determine age thresholds associated with symptom onset. The most frequently reported gastrointestinal complaints were abdominal bloating (50.8%), constipation (32.3%) and regurgitation (30.8%). Swallowing difficulties and prolonged meal times were significantly associated with older age and loss of ambulation. ROC analysis identified &gt;\u200914.5\u2009years as the age threshold for solid food dysphagia. A moderate, significant positive correlation was observed between MUAC\u2010Z and BMI\u2010SDS (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.520;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), whereas no significant association was found between TSF\u2010Z and BMI\u2010SDS. Vitamin D deficiency (&lt;\u200930\u2009ng\/mL) was widespread (86.2%) and more prevalent among non\u2010ambulatory patients (96.6% vs. 77.8%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.036). Malnutrition was more frequently observed in steroid\u2010na\u00efve children than in those receiving corticosteroid therapy (50% vs. 19%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.041). Nutritional deficiencies and gastrointestinal symptoms are commonly encountered in paediatric DMD and tend to increase with advancing age and functional decline. MUAC\u2010Z and TSF\u2010Z may offer complementary insights into muscle mass and fat distribution beyond BMI. These simple and non\u2010invasive measurements could be useful additions to routine nutritional surveillance in DMD management.\n                  <\/jats:p>","DOI":"10.1111\/jpc.70413","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T10:38:37Z","timestamp":1777977517000},"page":"936-943","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multifaceted Assessment of Nutritional Status and Gastrointestinal Health in Duchenne Muscular Dystrophy: Approaches Based on Skinfold Thickness and Mid\u2010Upper Arm Circumference"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3829-4978","authenticated-orcid":false,"given":"G\u00fcl","family":"\u00c7irkin","sequence":"first","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Gastroenterology, Hepatology and Nutrition Tepecik Training and Research Hospital  Izmir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8748-5586","authenticated-orcid":false,"given":"Yi\u011fithan","family":"G\u00fczin","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Neurology Tepecik Training and Research Hospital  Izmir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2913-717X","authenticated-orcid":false,"given":"Gizem","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Neurology Tepecik Training and Research Hospital  Izmir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5028-9995","authenticated-orcid":false,"given":"Gamze Sar\u0131kaya","family":"Uzan","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Neurology Tepecik Training and Research Hospital  Izmir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6853-6555","authenticated-orcid":false,"given":"Figen","family":"Baydan","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Neurology Tepecik Training and Research Hospital  Izmir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023\u2010017\u20100631\u20103"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.015151"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12277"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2011.05.011"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114510005030"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533615577931"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(18)30024\u20103"},{"key":"e_1_2_9_9_1","volume-title":"WHO Child Growth Standards: Growth Reference Data for 5\u201319\u2009Years","author":"World Health 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