{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:36:40Z","timestamp":1786988200535,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Early detection of insulin resistance (IR) in children is essential to prevent long\u2010term metabolic complications. Simple anthropometric measures\u2014mid\u2010upper arm circumference (MUAC) and skinfold thickness\u2014are widely used, but their predictive value, especially when age\u2010standardized, remains unclear. This study aimed to evaluate the performance of raw, SDS, and percentile MUAC and skinfold measurements in predicting IR in patients with obesity and adolescents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted with 171 participants with obesity aged 6\u201318\u2009years. Anthropometric measurements were recorded and converted to SDS and percentile values. Insulin resistance was evaluated using HOMA\u2010IR with pubertal\u2010stage\u2013adjusted cutoffs. Logistic regression and ROC analyses were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Insulin resistance was present in 56.1% of participants. Both MUAC and skinfold thickness showed significant positive associations with IR; however, standardized measures (SDS and percentiles) demonstrated markedly stronger predictive value than raw measurements. Skinfold thickness SDS emerged as the strongest independent predictor of IR (OR\u2009=\u200912.04,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), followed by MUAC SDS (OR\u2009=\u20097.28,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). ROC analysis showed excellent discriminatory power for skinfold SDS (AUC\u2009=\u20090.82), with an optimal cutoff of 1.48 (76% sensitivity, 80% specificity). MUAC SDS also performed well (AUC\u2009=\u20090.76; cutoff\u2009=\u20091.10).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Skinfold thickness SDS and MUAC SDS are strong, practical, and non\u2010invasive markers for predicting insulin resistance in paediatric patients with obesity. Standardized measurements clearly outperform raw values and should be integrated into routine clinical assessment to enhance early detection of metabolic risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.70456","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T04:17:19Z","timestamp":1780892239000},"page":"1482-1488","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Role of Skinfold Thickness and\n                    <scp>MUAC<\/scp>\n                    in Predicting Insulin Resistance:\n                    <scp>ROC<\/scp>\n                    And Regression Analysis"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1813-7780","authenticated-orcid":false,"given":"Neslihan","family":"G\u00fcrcan Kaya","sequence":"first","affiliation":[{"name":"Depatmament of Pediatric Gastroenterology Ankara Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5604-5759","authenticated-orcid":false,"given":"Yasemin","family":"Kinali \u00c7etin","sequence":"additional","affiliation":[{"name":"Depatmament of Pediatric Endocrinology Ankara Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/postgradmedj-2014-133033"},{"issue":"8","key":"e_1_2_10_3_1","first-page":"800","article-title":"Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta\u2010Analysis","volume":"178","author":"Zhang X.","year":"2024","journal-title":"Journal of American Medical Association Pediatrics"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031049"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0021-75572008000100009"},{"issue":"5","key":"e_1_2_10_6_1","first-page":"709","article-title":"Skinfold Equations for Estimation of Body Fatness in Children and Youth","volume":"60","author":"Slaughter M. 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