{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:36:36Z","timestamp":1786988196630,"version":"build-2736575974"},"reference-count":76,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long\u2010term implications for survival, kidney function, and long\u2010term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular filtration, makes this population vulnerable to AKI. Advances in consensus definitions, particularly the modified neonatal Kidney Disease Improving Global Outcomes (KDIGO) criteria, have enhanced epidemiologic understanding and facilitated global research collaboration. Despite this, significant variability in AKI surveillance, diagnosis, and follow\u2010up persists. Recent research efforts within Australia emphasize the need to incorporate AKI metrics into quality registries and improve equity of kidney care for infants. Integration of protocolized monitoring, preventative strategies such as nephrotoxin stewardship and methylxanthine therapy, and long\u2010term follow\u2010up for AKI survivors are essential to mitigating progression to chronic kidney disease. This narrative review synthesizes evolving evidence in neonatal renal physiology, AKI definition and biomarkers, epidemiology, management, and policy directions, emphasizing opportunities for education, protocol development, and collaborative improvement across Australia, New Zealand and beyond.<\/jats:p>","DOI":"10.1111\/jpc.70464","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:15:58Z","timestamp":1781068558000},"page":"1327-1334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal Acute Kidney Injury\u2014An Australian and New Zealand Perspective"],"prefix":"10.1111","volume":"62","author":[{"given":"Saumil","family":"Desai","sequence":"first","affiliation":[{"name":"Newborn Emergency Transport Services, Perth Children's Hospital  Nedlands Western Australia Australia"},{"name":"Neonatology Clinical Care Unit, Perth Children's Hospital  Nedlands Western Australia Australia"},{"name":"Centre for Neonatal Research and Education, University of Western Australia  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Forbes","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Melbourne Australia"},{"name":"Department of Nephrology Royal Children's Hospital  Melbourne Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon A.","family":"Carter","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Melbourne Australia"},{"name":"Department of Nephrology Royal Children's Hospital  Melbourne Australia"},{"name":"Department of Paediatrics University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison L.","family":"Kent","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Rochester  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanel","family":"Prestidge","sequence":"additional","affiliation":[{"name":"Department of Paediatric Nephrology Starship Children's Hospital  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Selewski","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Arkansas for Medica Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2917-1172","authenticated-orcid":false,"given":"Eveline","family":"Staub","sequence":"additional","affiliation":[{"name":"Department of Neonatology Royal North Shore Hospital  St Leonards New South Wales Australia"},{"name":"University of Sydney, Northern Clinical School, Royal North Shore Hospital  St Leonards New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8846-1650","authenticated-orcid":false,"given":"Anke","family":"Raaijmakers","sequence":"additional","affiliation":[{"name":"Paediatric Nephrology, Sydney Children's Hospital  Randwick Australia"},{"name":"School of Women's and Children's Health, University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(17)30069-X"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2369-4"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-021-05251-0"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2023-065182"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l1346"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.13461118"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.24270"},{"issue":"2","key":"e_1_2_16_9_1","first-page":"676","article-title":"Premature Infants Born <\u200928\u2009Weeks With Acute Kidney Injury Have Increased Bronchopulmonary Dysplasia Rates","volume":"94","author":"Starr M. 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