{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T04:57:04Z","timestamp":1790571424875,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Acute obstructive lower airway disease (AOLAD) is a common cause of paediatric respiratory distress, yet early predictors of escalation beyond low\u2010flow oxygen are limited. We aimed to identify admission factors associated with the need for noninvasive respiratory support (NRS; HFNC and\/or nasal CPAP\/BiPAP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective observational study conducted in a tertiary paediatric intensive care unit in T\u00fcrkiye (January 2020 and January 2025) including children aged 1\u2009month to 5\u2009years with AOLAD; pneumonia and asthma were excluded. Demographics, admission vital signs, laboratory values (including serum magnesium) and chest imaging findings were abstracted from electronic records. Univariable analyses reported crude associations, and multivariable logistic regression included prespecified clinically relevant covariates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 338 children (median age 11\u2009months), 172 (50.9%) received NRS. In multivariable analysis, hypomagnesemia (OR 6.56; 95% CI 3.28\u201313.12), tachypnea (OR 2.40; 95% CI 1.29\u20134.46), acidosis (OR 2.01; 95% CI 1.15\u20133.54) and younger age (OR 0.98 per month; 95% CI 0.96\u20130.99) were independently associated with NRS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hypomagnesemia is a readily measurable marker associated with NRS requirement in paediatric AOLAD and may complement bedside assessment. Serum magnesium should be considered in the admission workup of patients with AOLAD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jpc.70506","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T13:12:42Z","timestamp":1784380362000},"page":"1663-1668","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypomagnesemia as a Predictor of Noninvasive Respiratory Support in Children With Acute Obstructive Lower Airway Disease: A Retrospective\n                    <scp>PICU<\/scp>\n                    Cohort Study"],"prefix":"10.1111","volume":"62","author":[{"given":"K\u0131van\u00e7","family":"Terzi","sequence":"first","affiliation":[{"name":"Department of Pediatric Intensive Care A\u011fr\u0131 Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5449-0125","authenticated-orcid":false,"given":"Fatma G\u00fcl","family":"Ersan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care A\u011fr\u0131 Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.33804"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(24)00176\u20102"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8844420"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001883"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/jopp.jopp_11_24"},{"key":"e_1_2_12_7_1","volume-title":"Nelson Textbook of Pediatrics: Volume 1\u20132","author":"Lo S. F.","year":"2024"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000905"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000432"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201051214\u20104"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jointm.2024.09.001"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/children8080719"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_490_19"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25169"}],"container-title":["Journal of Paediatrics and Child Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.70506","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jpc.70506","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpc.70506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T04:46:43Z","timestamp":1790570803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpc.70506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,18]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/jpc.70506"],"URL":"https:\/\/doi.org\/10.1111\/jpc.70506","archive":["Portico"],"relation":{},"ISSN":["1034-4810","1440-1754"],"issn-type":[{"value":"1034-4810","type":"print"},{"value":"1440-1754","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,18]]},"assertion":[{"value":"2026-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}