{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:47:36Z","timestamp":1789523256660,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003758","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Maranh\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Public Health Dent"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study investigated regional trends in delays between the histological diagnosis of oral and oropharyngeal cancer and initiation of treatment across Brazil's federal units from 2013 to 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective, observational study was conducted using secondary data from the Brazilian Health System Database (DATASUS) for the years 2013\u20132019. Variables collected included the year of treatment, sex, age group, anatomical location, disease stage, treatment method, and federal unit of Brazil. Thematic maps were generated, and time series were analyzed using joint\u2010point regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 72,062 cases were included in the study. Majority of cases were of men (79.32%) and individuals older than 45\u2009years (91.15%). Treatment was initiated earlier in younger patients, in cases of lip cancer, and among those who had undergone surgery. In 11 states, a significant decrease was observed in initiating treatment for oral cancer 60\u2009days from diagnosis, whereas a significant increase was observed in three states. For oropharyngeal cancer, a significant decrease was observed in initiating treatment at 60\u2009days from diagnosis in three states, whereas a significant increase was observed in five states.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings revealed a high degree of heterogeneity in treatment delays for oral and oropharyngeal cancer across Brazil from 2013 to 2019. The northern states of Brazil exhibited a high percentage of treatment delays exceeding 60\u2009days.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jphd.12658","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:04:38Z","timestamp":1738825478000},"page":"102-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Temporal trends in treatment delays for oral and oropharyngeal cancer in Brazil: An analysis of the national database"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6401-1513","authenticated-orcid":false,"given":"Marcio Vin\u00edcius Campos","family":"Borges","sequence":"first","affiliation":[{"name":"Dentistry Graduate Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2247-0017","authenticated-orcid":false,"given":"Erika Martins","family":"Pereira","sequence":"additional","affiliation":[{"name":"Dentistry Graduate Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4162-1711","authenticated-orcid":false,"given":"Raysa Theresa Pinheiro","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology University of Sao Paulo School of Dentistry  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8027-3372","authenticated-orcid":false,"given":"Izabel Cristina Vieira","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Dentistry Graduate Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4156-4067","authenticated-orcid":false,"given":"Erika Barbara Abreu Fonseca","family":"Thomaz","sequence":"additional","affiliation":[{"name":"Dentistry Graduate Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"},{"name":"Department of Public Health Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6785-7864","authenticated-orcid":false,"given":"Vandilson","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Dentistry Graduate Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"International Agency for Research on Cancer (IARC)\/World Health Organization (WHO).Global Cancer Observatory: Cancer Today. Lip oral cavity.2024Available from:https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/cancers\/1\u2010lip\u2010oral\u2010cavity\u2010fact\u2010sheet.pdf. Accessed 27 Aug 2024"},{"key":"e_1_2_8_3_1","unstructured":"International Agency for Research on Cancer (IARC)\/World Health Organization (WHO).Global Cancer Observatory: Cancer Today. Oropharynx.2024Available from:https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/cancers\/3\u2010oropharynx\u2010fact\u2010sheet.pdf. Accessed 27 Aug 2024"},{"key":"e_1_2_8_4_1","unstructured":"International Agency for Research on Cancer (IARC)\/World Health Organization (WHO).Global Cancer Observatory: Cancer Today. Brazil.2024Available from:https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/populations\/76\u2010brazil\u2010fact\u2010sheet.pdf. 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