{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T19:27:42Z","timestamp":1787686062800,"version":"build-2784847793"},"reference-count":141,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T00:00:00Z","timestamp":1480032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004699","name":"Chung Shan Medical University Hospital","doi-asserted-by":"publisher","award":["CSH\u20102016\u2010E\u2010002\u2010Y2"],"award-info":[{"award-number":["CSH\u20102016\u2010E\u2010002\u2010Y2"]}],"id":[{"id":"10.13039\/501100004699","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pineal Research"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Melatonin is a naturally occurring molecule secreted by the pineal gland and known as a gatekeeper of circadian clocks. Mounting evidence indicates that melatonin, employing multiple and interrelated mechanisms, exhibits a variety of oncostatic properties in a myriad of tumors during different stages of their progression. Tumor metastasis, which commonly occurs at the late stage, is responsible for the majority of cancer deaths; metastases lead to the development of secondary tumors distant from a primary site. In reference to melatonin, the vast majority of investigations have focused on tumor development and progression at the primary site. Recently, however, interest has shifted toward the role of melatonin on tumor metastases. In this review, we highlight current advances in understanding the molecular mechanisms by which melatonin counteracts tumor metastases, including experimental and clinical observations; emphasis is placed on the impact of both cancer and non\u2010neoplastic cells within the tumor microenvironment. Due to the broad range of melatonin's actions, the mechanisms underlying its ability to interfere with metastases are numerous. These include modulation of cell\u2013cell and cell\u2013matrix interaction, extracellular matrix remodeling by matrix metalloproteinases, cytoskeleton reorganization, epithelial\u2013mesenchymal transition, and angiogenesis. The evidence discussed herein will serve as a solid foundation for urging basic and clinical studies on the use of melatonin to understand and control metastatic diseases.<\/jats:p>","DOI":"10.1111\/jpi.12370","type":"journal-article","created":{"date-parts":[[2016,10,12]],"date-time":"2016-10-12T19:55:10Z","timestamp":1476302110000},"source":"Crossref","is-referenced-by-count":231,"title":["Cancer metastasis: Mechanisms of inhibition by melatonin"],"prefix":"10.1111","volume":"62","author":[{"given":"Shih\u2010Chi","family":"Su","sequence":"first","affiliation":[{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases Chang Gung Memorial Hospital Keelung Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital Taipei Linkou and Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Ju","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Cancer Research Center Changhua Christian Hospital Changhua Taiwan"},{"name":"Institute of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Graduate Institute of Biomedical Sciences China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010En","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Department of Medical Research Chung Shan Medical University Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Hung","family":"Chung","sequence":"additional","affiliation":[{"name":"Whole\u2010Genome Research Core Laboratory of Human Diseases Chang Gung Memorial Hospital Keelung Taiwan"},{"name":"Department of Dermatology Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital Taipei Linkou and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russel J.","family":"Reiter","sequence":"additional","affiliation":[{"name":"Department of Cellular and Structural Biology The University of Texas Health Science Center San Antonio TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun\u2010Fa","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Medicine Chung Shan Medical University Taichung Taiwan"},{"name":"Department of Medical Research Chung Shan Medical University Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2727"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.02.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc865"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-2407"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3125"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2618"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja01543a060"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-0694fje"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00931.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-014-1579-2"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00856.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12221"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)81008-4"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.01.004"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00011.2014"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12224"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2004.05.002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2010.12.004"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00909.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)61934-4"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.13.7037"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(98)00179-9"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(19970601)65:3<430::AID-JCB12>3.0.CO;2-J"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2004.00141.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01923944"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M403140200"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2007.00513.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2016.1091882"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.1993.tb00498.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12196"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12267"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12360"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10102-010-0030-2"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1385\/ENDO:27:2:119"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12026"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00934.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms151223448"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2011.586365"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1385\/ENDO:27:2:201"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12227"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-15-0030"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12240"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12257"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12348"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12330"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12302"},{"key":"e_1_2_7_48_1","first-page":"2747","article-title":"Role of melatonin in cancer treatment","volume":"32","author":"Cutando A","year":"2012","journal-title":"Anticancer Res"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2013.834890"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12226"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8776"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2004.00165.x"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986710794183015"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2005.00258.x"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-419X(01)00038-5"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-2938"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(00)00158-1"},{"key":"e_1_2_7_59_1","first-page":"4383","article-title":"Influence of melatonin on invasive and metastatic properties of MCF\u20107 human breast cancer cells","volume":"58","author":"Cos S","year":"1998","journal-title":"Cancer Res"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12295"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2008.11.005"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101132"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.12.008"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00971-6"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-015-0454-8"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.07.011"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-011-1024-y"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2621"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3904"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1208324109"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(00)01676-X"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1693"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2010.00812.x"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12034"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/35036374"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-006-7886-9"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12308"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8009"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12365"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-008-9166-3"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12704"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.100115"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2008.00600.x"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-015-0382-6"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12270"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871520614666140812110246"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2003.06.005"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-015-0048-3"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2015.1063296"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02552"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3758"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38019"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.11.007"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1234850"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00323-08"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(01)00260-X"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208429"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.1.306-319.2004"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm757"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21695"},{"key":"e_1_2_7_101_1","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1016\/S0021-9258(18)53979-X","article-title":"Activation of the human vimentin gene by the Tax human T\u2010cell leukemia virus. I. Mechanisms of regulation by the NF\u2010kappa B transcription factor","volume":"268","author":"Lilienbaum A","year":"1993","journal-title":"J Biol Chem"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209808"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1559"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150407"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1201012"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(20000415)86:2<188::AID-IJC7>3.0.CO;2-W"},{"key":"e_1_2_7_107_1","first-page":"353","article-title":"Transcriptional up\u2010regulation of matrix metalloproteinase\u20109 expression during spontaneous epithelial to neuroblast phenotype conversion by SK\u2010N\u2010SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT\u2010box and nuclear factor kappaB elements","volume":"10","author":"Farina AR","year":"1999","journal-title":"Cell Growth Differ"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.09.013"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2012-1071"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-16-0158"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/743193"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161209788453275"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2007.04.001"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2011.01.015"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113199990590"},{"key":"e_1_2_7_116_1","first-page":"45","article-title":"Anti\u2010angiogenic activity of melatonin in advanced cancer patients","volume":"22","author":"Lissoni P","year":"2001","journal-title":"Neuro Endocrinol Lett"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2012.01030.x"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12052"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.9591"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2015.4238"},{"key":"e_1_2_7_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2016.02.004"},{"key":"e_1_2_7_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-2760(02)00010-3"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64807-9"},{"key":"e_1_2_7_124_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202421200"},{"key":"e_1_2_7_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12131"},{"key":"e_1_2_7_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2013.02.008"},{"key":"e_1_2_7_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2007.00496.x"},{"key":"e_1_2_7_128_1","doi-asserted-by":"publisher","DOI":"10.1530\/JOE-12-0147"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1469"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00145.2015"},{"key":"e_1_2_7_131_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164853"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-1995"},{"key":"e_1_2_7_133_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI43424"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(09)02003-X"},{"key":"e_1_2_7_135_1","doi-asserted-by":"publisher","DOI":"10.18632\/genesandcancer.107"},{"key":"e_1_2_7_136_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986710791233689"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1211\/002235702760345374"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-1776"},{"key":"e_1_2_7_139_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2794"},{"key":"e_1_2_7_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2009.06.016"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2009.00727.x"},{"key":"e_1_2_7_142_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12158"}],"container-title":["Journal of Pineal Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjpi.12370","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpi.12370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T11:58:11Z","timestamp":1719921491000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpi.12370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,25]]},"references-count":141,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/jpi.12370"],"URL":"https:\/\/doi.org\/10.1111\/jpi.12370","archive":["Portico"],"relation":{},"ISSN":["0742-3098","1600-079X"],"issn-type":[{"value":"0742-3098","type":"print"},{"value":"1600-079X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,25]]},"article-number":"e12370"}}