{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:22:32Z","timestamp":1777357352779,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Faculty of Veterinary Medicine (Urmia University-Iran)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This study aimed to evaluate the effects of supplementing a basal diet (<jats:styled-content style=\"fixed-case\">CTR<\/jats:styled-content>) with raw garlic (<jats:styled-content style=\"fixed-case\">GAR<\/jats:styled-content>) or garlic oil (<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>) on blood profile in sheep. Monensin (<jats:styled-content style=\"fixed-case\">MON<\/jats:styled-content>, 33\u00a0mg\/kg<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>) was used as positive control. Four ruminally fistulated rams were used in three experiments each arranged in a 4\u00a0\u00d7\u00a04 Latin square design with 28\u2010day periods. Experiments 1 and 2 differed in the dose of<jats:styled-content style=\"fixed-case\">GAR<\/jats:styled-content>(75 vs. 100\u00a0g\/kg<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>) and<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>(500 vs. 750\u00a0mg\/kg<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>), while experiment 3 was designed to compare the two doses of each additive (<jats:styled-content style=\"fixed-case\">GAR<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>). The animals were fed a basal diet as<jats:styled-content style=\"fixed-case\">TMR<\/jats:styled-content>consisting of 77.83% forage (alfalfa hay and corn silage) and 22.17% concentrate, providing 10.50\u00a0MJ\/kg<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>(metabolizable energy) and 16.5% crude protein to cover maintenance energy and protein requirements. Supplementation of monensin decreased (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05)<jats:italic>\u03b2<\/jats:italic>\u2010hydroxybutyrate (<jats:styled-content style=\"fixed-case\">BHB<\/jats:styled-content>) and non\u2010esterified fatty acid (<jats:styled-content style=\"fixed-case\">NEFA<\/jats:styled-content>) concentrations in the blood compared with other treatments. There was no significant effect of additives on serum concentration of glucose, total triglycerides, cholesterol, total protein, albumin and blood urea nitrogen (<jats:styled-content style=\"fixed-case\">BUN<\/jats:styled-content>). Although the serum insulin concentration was elevated in sheep receiving<jats:styled-content style=\"fixed-case\">MON<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>(<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01), no change was observed in blood glucose concentration. No significant effect of<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">GAR<\/jats:styled-content>was observed in key energy and protein\u2010related blood metabolites. However, administration of monensin had a positive influence on energy indices. In conclusion, whereas parameters characterizing the energy balance did not show a significant effect of<jats:styled-content style=\"fixed-case\">GAR<\/jats:styled-content>supplementation, a higher insulin concentration in<jats:styled-content style=\"fixed-case\">GAO<\/jats:styled-content>\u2010treated animals was observed.<\/jats:p>","DOI":"10.1111\/jpn.12189","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T13:32:19Z","timestamp":1396359139000},"page":"114-122","source":"Crossref","is-referenced-by-count":14,"title":["Changes in blood profile in sheep receiving raw garlic, garlic oil or monensin"],"prefix":"10.1111","volume":"99","author":[{"given":"E.","family":"Anassori","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Urmia University Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Dalir\u2010Naghadeh","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Urmia University Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pirmohammadi","sequence":"additional","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture Urmia University Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hadian","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Urmia University Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Regulation 1831\/2003\/EC on additives for use in animal nutrition replacing Directive 70\/524\/EEC on additives in feeding\u2010stuffs"},{"key":"e_1_2_7_3_1","first-page":"787","article-title":"Nutritive requirements of ruminant animals, Protein","volume":"62","author":"AFRC","year":"1992","journal-title":"Nutrition Abstracts and Reviews (Series B)"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2011.08.003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1095-6433(03)00114-4"},{"key":"e_1_2_7_6_1","volume-title":"Official Methods of Analysis","author":"AOAC","year":"1990"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0367-326X(03)00158-8"},{"key":"e_1_2_7_8_1","first-page":"865","article-title":"Glucose metabolism in ruminants as related to hypoglycemia and ketosis","volume":"215","author":"Bergman E. 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