{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T19:32:39Z","timestamp":1790451159861,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,1,8]],"date-time":"2017-01-08T00:00:00Z","timestamp":1483833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009997","name":"Earmarked Fund for Modern Agro-industry Technology Research System","doi-asserted-by":"crossref","award":["CARS-44-B-1"],"award-info":[{"award-number":["CARS-44-B-1"]}],"id":[{"id":"10.13039\/501100009997","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100010042","name":"Special Fund for Agro-scientific Research in the Public Interest","doi-asserted-by":"crossref","award":["2000903006"],"award-info":[{"award-number":["2000903006"]}],"id":[{"id":"10.13039\/501100010042","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The objective of this experiment was to investigate the effect of <jats:italic>Lactobacillus<\/jats:italic> isolates on intestinal bacterial community composition of growing Rex Rabbits. A total of 120 weaned Rex Rabbits (30\u00a0days old, 30 per group) were used for the experiment, which started after an adaptation period of 7\u00a0days. The control group was fed with basal diet only, while the treatment I, <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> groups were fed with basal diet adding antibiotics, <jats:italic>Lactobacillus zeae<\/jats:italic> (<jats:styled-content style=\"fixed-case\">LB<\/jats:styled-content>1) and <jats:italic>Lactobacillus casei<\/jats:italic> (L3) respectively. Growth performance, immune response and intestinal flora have been examined. The results obtained were as follows: (i) F\/G of the rabbits fed with <jats:italic>Lactobacillus<\/jats:italic> isolates was significantly lower than that of the control group (p\u00a0&lt;\u00a00.05). (ii) The concentration of <jats:styled-content style=\"fixed-case\">ALT<\/jats:styled-content> decreased significantly (p\u00a0&lt;\u00a00.05) and that of IgG and IgM increased significantly (p\u00a0&lt;\u00a00.05) after feeding rabbits with <jats:italic>Lactobacillus<\/jats:italic> isolates. (iii) <jats:italic>Lactobacillus<\/jats:italic> isolates had no influence on the number of mast cells in duodenum and jejunum, but increased the number of mast cells in caecum significantly (p\u00a0&lt;\u00a00.05). (iv) The data from pyrosequencing\u2010based analysis suggested that the bacterial community in the rabbit's intestinal flora can be changed by <jats:italic>Lactobacillus<\/jats:italic> isolates and antibiotics, especially for the microbial diversity and abundance in the caecum. In conclusion, the application of proper <jats:italic>Lactobacillus<\/jats:italic> isolates can improve the growth performance, enhance the immunological function and adjust the intestinal micro\u2010ecosystem of growing Rex Rabbits.<\/jats:p>","DOI":"10.1111\/jpn.12629","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T03:57:05Z","timestamp":1483934225000},"source":"Crossref","is-referenced-by-count":32,"title":["The Effect of <i>Lactobacillus<\/i> isolates on growth performance, immune response, intestinal bacterial community composition of growing Rex Rabbits"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2036-3100","authenticated-orcid":false,"given":"C.","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Animal Science Shandong Agricultural University Taian Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Animal Science Shandong Agricultural University Taian Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Animal Science Shandong Agricultural University Taian Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Animal Science Shandong Agricultural University Taian Shandong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2007.00746.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/584183"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2095-3119(14)60827-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12242"},{"key":"e_1_2_6_6_1","volume-title":"Nutrition of the Rabbit","author":"Blas C.","year":"1998"},{"key":"e_1_2_6_7_1","first-page":"53","article-title":"Regulative mechanism of local immunity in rat mammary gland \u2010distribution of mast cells in mammary gland during lactating and non\u2010lactating periods","volume":"2","author":"Chao G.","year":"2005","journal-title":"The Journal of Veterinary Science"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6941.2011.01148.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005963107"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mbo3.178"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-8-125"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2006.09.005"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1079\/ASC41570281"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2007.08.025"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731112000389"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-013-1268-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1184"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.2004.401"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2012.08.014"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6941.2009.00812.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.4161\/19490976.2014.969972"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.05.021"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2012.01.012"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6941.2010.00980.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2011.05.003"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05010"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20908"},{"key":"e_1_2_6_28_1","unstructured":"Massip K.;Combes S.;Cauquil L.;Zemb O.;Gidenne T. 2012:High throughput 16S\u2010DNA sequencing for phylogenetic affiliation of the caecal bacterial community in the rabbit impact of the hygiene of housing and of the intake level. 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