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Pork is the third most important cause for outbreak\u2010associated salmonellosis, and colibacillosis is the most important disease in piglets and swine. Attachment to host cells, translocation of effector proteins into host cells, invasion and replication in tissues are the vital virulence steps of these pathogens that help them to thrive in the intestinal environment and invade tissues. Feed contamination is an important source for<jats:italic>Salmonella<\/jats:italic>infection in pig production. Many on\u2010farm feeding strategies intervene to avoid the introduction of pathogens onto the farm by contaminated feeds or to reduce infection pressure when pathogens are present. Among the latter, prebiotics could be effective at protecting against these enteric bacterial pathogens. Nowadays, a wide range of molecules can potentially serve as prebiotics. Here, we summarize the prevalence of<jats:italic>Salmonella<\/jats:italic>sp. and<jats:italic>Escherichia\u00a0coli in pigs<\/jats:italic>, understanding of the mechanisms by which pathogens can cause disease, the feed related to pathogen contamination in pigs and detail the mechanisms on which prebiotics are likely to act in order to fulfil their protective action against these pathogens in pig production. Many different mechanisms involve the inhibition of<jats:italic>Salmonella<\/jats:italic>and<jats:italic>E.\u00a0coli<\/jats:italic>by prebiotics such as coating the host surface, modulation of intestinal ecology, downregulating the expression of adhesin factors or virulence genes, reinforcing the host immune system.<\/jats:p>","DOI":"10.1111\/jpn.12666","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T07:01:23Z","timestamp":1482908483000},"page":"17-32","source":"Crossref","is-referenced-by-count":75,"title":["Review on the effects of potential prebiotics on controlling intestinal enteropathogens<i>Salmonella<\/i>and<i>Escherichia\u00a0coli<\/i>in pig production"],"prefix":"10.1111","volume":"102","author":[{"given":"T. H. 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