{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T09:03:18Z","timestamp":1779267798922,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T00:00:00Z","timestamp":1488758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DA 558\/1\u20104"],"award-info":[{"award-number":["DA 558\/1\u20104"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Summary<\/jats:title>We studied the constancy of the relationship between rectal and intraabdominal temperature as well as their linkage to inflammatory markers (leucocyte counts, kynurenine\u2010to\u2010tryptophan ratio (Kyn\u2013Trp ratio), tumour necrosis factor alpha (TNF<\/jats:styled-content>\u2010\u03b1<\/jats:italic>) in healthy and in pigs exposed to lipopolysaccharide (LPS<\/jats:styled-content>) and\/or deoxynivalenol (DON<\/jats:styled-content>). Barrows (n<\/jats:italic>\u00a0=\u00a044) were fed 4\u00a0weeks either a DON<\/jats:styled-content>\u2010contaminated\u00a0(4.59\u00a0mg DON<\/jats:styled-content>\/kg feed)\u00a0or a control (CON<\/jats:styled-content>) diet and\u00a0equipped with an\u00a0intraabdominal\u00a0temperature logger and a multicatheter system (V.portae\u00a0hepatis, V.lienalis, Vv.jugulares)<\/jats:italic> facilitating infusion of 0.9% NaCl (CON<\/jats:styled-content>) or LPS<\/jats:styled-content>\u00a0(7.5\u00a0\u03bc<\/jats:italic>g\/kg\u00a0BW<\/jats:styled-content>) and simultaneous blood sampling. Body temperatures were measured and blood samples taken every 15\u00a0min for leucocyte counts, TNF<\/jats:styled-content>\u2010\u03b1<\/jats:italic> and Kyn\u2013Trp ratio. Combination of diet and infusion created six groups: CON<\/jats:styled-content>_CON<\/jats:styled-content>jug<\/jats:sub>.\u2010CON<\/jats:styled-content>por.<\/jats:sub>, CON<\/jats:styled-content>_CON<\/jats:styled-content>jug.<\/jats:sub>\u2010LPS<\/jats:styled-content>por.<\/jats:sub>, CON<\/jats:styled-content>_LPS<\/jats:styled-content>jug.<\/jats:sub>\u2010CON<\/jats:styled-content>por.<\/jats:sub>, DON<\/jats:styled-content>_CON<\/jats:styled-content>jug.<\/jats:sub>\u2010CON<\/jats:styled-content>por.<\/jats:sub>, DON<\/jats:styled-content>_CON<\/jats:styled-content>jug.<\/jats:sub>\u2010LPS<\/jats:styled-content>por.<\/jats:sub>, DON<\/jats:styled-content>_LPS<\/jats:styled-content>jug.<\/jats:sub>\u2010CON<\/jats:styled-content>por.<\/jats:sub>. The relationship between both temperatures was not uniform for all conditions. Linear regression revealed that an intraabdominal increase per 1\u00b0C increase in rectal temperature was ~25% higher in all LPS<\/jats:styled-content>\u2010infused pigs compared to NaCl\u2010infusion, albeit diet and site of LPS<\/jats:styled-content> infusion modified the magnitude of this difference. Inflammatory markers were only strongly present under LPS<\/jats:styled-content> influence and showed a significant relationship with body temperatures. For example, leucocyte counts in clinically inconspicuous animals were only significantly correlated to core temperature in DON<\/jats:styled-content>\u2010fed pigs, but in all LPS<\/jats:styled-content>\u2010infused groups, irrespective of diet and temperature method. In conclusion, the gradient between body core and rectal temperature is constant in clinically inconspicuous pigs, but not under various pathophysiological conditions. In the latter, measurement of inflammatory markers seems to be a useful completion.<\/jats:p>","DOI":"10.1111\/jpn.12684","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T11:07:02Z","timestamp":1488798422000},"page":"241-251","source":"Crossref","is-referenced-by-count":17,"title":["Relationships between body temperatures and inflammation indicators under physiological and pathophysiological conditions in pigs exposed to systemic lipopolysaccharide and dietary deoxynivalenol"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5149-1343","authenticated-orcid":false,"given":"T.","family":"Tesch","sequence":"first","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bannert","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kluess","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Frahm","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"H\u00fcther","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kersten","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Breves","sequence":"additional","affiliation":[{"name":"Institute for Physiology University of Veterinary Medicine Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Renner","sequence":"additional","affiliation":[{"name":"Institute of Anatomy Otto von Guericke University Magdeburg Magdeburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kahlert","sequence":"additional","affiliation":[{"name":"Institute of Anatomy Otto von Guericke University Magdeburg Magdeburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.\u2010J.","family":"Rothk\u00f6tter","sequence":"additional","affiliation":[{"name":"Institute of Anatomy Otto von Guericke University Magdeburg Magdeburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"D\u00e4nicke","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Federal Research Institute for Animal Health Friedrich\u2010Loeffler\u2010Institute Braunschweig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins7114773"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(96)00990-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800620802"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/84.5.615"},{"issue":"5","key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.3357\/ASEM.2655.2010","article-title":"Core temperature influences on the relationship between exercise\u2010induced leukocytosis and cortisol or TNF\u2010alpha","volume":"81","author":"Cooper E. 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