{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T12:55:28Z","timestamp":1762520128655,"version":"3.37.3"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T00:00:00Z","timestamp":1494806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2016J01698"],"award-info":[{"award-number":["2016J01698"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005270","name":"Fujian Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["JA15190"],"award-info":[{"award-number":["JA15190"]}],"id":[{"id":"10.13039\/501100005270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Summary<\/jats:title>This study was designed to investigate effects of xanthophylls on serum lipid profile (triglyceride, TG<\/jats:styled-content>; cholesterol, CHO<\/jats:styled-content>; high\u2010density lipoprotein cholesterol, HDLC<\/jats:styled-content>; and low\u2010density lipoprotein cholesterol, LDLC<\/jats:styled-content>) and nuclear factor (peroxisome proliferator\u2010activated receptor gamma, PPAR<\/jats:styled-content>\u03b3; PPAR<\/jats:styled-content> gamma coactivator 1 alpha, PGC<\/jats:styled-content>1\u03b1; retinoid X receptor gamma, RXR<\/jats:styled-content>\u03b3; and retinoic acid receptor alpha, RAR<\/jats:styled-content>\u03b1) gene expression of breeding hens and chicks. In experiment 1, 432 hens were divided into three groups and fed diets supplemented with 0 (as control group), 20 or 40\u00a0mg\/kg xanthophylls. Blood was sampled at 7, 14, 21, 28 and 35 days of trial. Liver, duodenum, jejunum and ileum were sampled at 35 days of trial. Results showed that serum HDLC<\/jats:styled-content> level of hens was increased after dietary 40\u00a0mg\/kg xanthophyll addition for 21, 28 and 35 days, while serum TG<\/jats:styled-content>, CHO<\/jats:styled-content> and LDLC<\/jats:styled-content> were not affected. Xanthophyll addition also increased PPAR<\/jats:styled-content>\u03b3 expression in jejunum, RXR<\/jats:styled-content>\u03b3 expression in duodenum and jejunum, and RAR<\/jats:styled-content>\u03b1 expression in liver and duodenum. Experiment 2 was a 2\u00a0\u00d7\u00a02 factorial design. Male chicks hatched from 0 or 40\u00a0mg\/kg xanthophyll diet of hens were fed diet containing either 0 or 40\u00a0mg\/kg xanthophylls. Liver, duodenum, jejunum and ileum were sampled at 0, 7, 14 and 21 days after hatching. Blood samples were also collected at 21 days. Results showed that in ovo xanthophylls elevated PPAR<\/jats:styled-content>\u03b3 in duodenum and jejunum, and RXR<\/jats:styled-content>\u03b3 and RAR<\/jats:styled-content>\u03b1 in liver of chicks mainly within 1\u00a0week after hatching, while dietary xanthophylls increased serum HDLC<\/jats:styled-content> level and PPAR<\/jats:styled-content>\u03b3 and RXR<\/jats:styled-content>\u03b3 in liver from 2\u00a0weeks onwards. In conclusion, our research suggested xanthophylls can regulate serum lipid profile and nuclear factor expression in hens and chicks.<\/jats:p>","DOI":"10.1111\/jpn.12739","type":"journal-article","created":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T05:26:46Z","timestamp":1494826006000},"source":"Crossref","is-referenced-by-count":3,"title":["Xanthophylls increased HDLC<\/scp> level and nuclear factor PPAR<\/scp>\u03b3, RXR<\/scp>\u03b3 and RAR<\/scp>\u03b1 expression in hens and chicks"],"prefix":"10.1111","volume":"102","author":[{"given":"Y.\u2010Y.","family":"Gao","sequence":"first","affiliation":[{"name":"College of Animal Science Fujian Agriculture and Forestry University Fuzhou Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Jin","sequence":"additional","affiliation":[{"name":"China National Engineering Research Center of JUNCAO Technology Fujian Agriculture and Forestry University Fuzhou Fujian 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