{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:26:33Z","timestamp":1787624793149,"version":"build-2736575974"},"reference-count":54,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T00:00:00Z","timestamp":1501718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Scientific Research Foundation for Returned Overseas Chinese Scholars"},{"name":"State Education Ministry"},{"name":"Chang-jiang Scholars and Innovative Research Team of the University of China","award":["ITT0848"],"award-info":[{"award-number":["ITT0848"]}]},{"name":"International Cooperative Project of Science and Technology Bureau of Sichuan Province","award":["2013HH0055"],"award-info":[{"award-number":["2013HH0055"]}]},{"name":"Chengdu Agricultural Technology Research and Development Project","award":["2015-NY02-00295-NC"],"award-info":[{"award-number":["2015-NY02-00295-NC"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Summary<\/jats:title>Probiotics promote the health of the host by maintaining intestinal microbial homeostasis. This study aimed to investigate the benefits of Lactobacillus plantarum <\/jats:italic>BS<\/jats:styled-content>22 (LP<\/jats:styled-content>) in the gastrointestinal tract (GIT<\/jats:styled-content>) microbial homeostasis of broiler chickens exposed to aflatoxin B1<\/jats:sub> using the PCR<\/jats:styled-content>\u2010DGGE<\/jats:styled-content>, viable count and real\u2010time PCR<\/jats:styled-content>. The toxin adsorption experiment demonstrated that treatment R5 (1.0\u00a0\u00d7\u00a0108<\/jats:sup> CFU<\/jats:styled-content>\/g LP<\/jats:styled-content>) exhibited good absorptive effect in adsorbing the aflatoxin B1<\/jats:sub> (AFB<\/jats:styled-content>1<\/jats:sub>) in vitro. DGGE<\/jats:styled-content> showed that the composition and structure of gut microbiota were more similar in the mucosa than in the content of all the samples. In addition, higher diversity of the microbiota was observed in the caecum and glandular stomach than in other segments. Lactobacillus<\/jats:italic>, Enterococcus<\/jats:italic> and Enterobacteriaceae<\/jats:italic> were more abundant in the ileum than in the other segments. Enterobacteriaceae<\/jats:italic> in groups I (basal diet) and II<\/jats:styled-content> (basal diet+50\u00a0\u03bcg\/kg AFB<\/jats:styled-content>1<\/jats:sub>) showed a significant difference in group III<\/jats:styled-content> (basal diet + 50 \u03bcg\/kg AFB<\/jats:styled-content>1<\/jats:sub>\u00a0+\u00a01\u00a0\u00d7\u00a0108<\/jats:sup> CFU<\/jats:styled-content>\/g LP<\/jats:styled-content>) in the crop content and duodenum mucosa (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>.05). This investigation indicates that the L. plantarum <\/jats:italic>BS<\/jats:styled-content>22 promotes GIT<\/jats:styled-content> microbial homeostasis in broiler chickens exposed to AFB<\/jats:styled-content>1<\/jats:sub>, particularly for the intestine mucosa microbiota. Thus, L. plantarum <\/jats:italic>BS<\/jats:styled-content>22 is a possible candidate for degrading AFB<\/jats:styled-content>1.<\/jats:sub><\/jats:p>","DOI":"10.1111\/jpn.12766","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T20:22:40Z","timestamp":1501791760000},"source":"Crossref","is-referenced-by-count":22,"title":["Lactobacillus plantarum <\/i>BS<\/scp>22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1<\/sub>"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1731-9179","authenticated-orcid":false,"given":"Y.","family":"Zeng","sequence":"first","affiliation":[{"name":"Animal Microecology Institute College of Veterinary Medicine Sichuan Agricultural University Sichuan China"},{"name":"Key Laboratory of Animal Disease and Human Health of Sichuan Province Sichuan Agricultural University Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Zeng","sequence":"additional","affiliation":[{"name":"Animal Microecology Institute College of Veterinary Medicine Sichuan Agricultural University Sichuan China"},{"name":"Key Laboratory of Animal Disease and Human Health of Sichuan Province Sichuan Agricultural University Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Animal Microecology Institute College of Veterinary Medicine Sichuan Agricultural University Sichuan China"},{"name":"Key Laboratory of Animal Disease and Human Health of Sichuan Province Sichuan Agricultural University Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. 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