{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T16:36:28Z","timestamp":1785342988318,"version":"3.55.0"},"reference-count":45,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T00:00:00Z","timestamp":1499644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Consumption of a second meal of colostrum with high quality could contribute to the intestinal epithelium development, especially if there is poor supply of colostrum just after birth. The effect of a second colostrum meal was evaluated on histomorphometry of the intestinal mucosa of newborn Holstein calves fed with high\u2010 and low\u2010quality first colostrum. Seventy\u2010two calves were fed with a first colostrum meal with high (<jats:styled-content style=\"fixed-case\">HFM<\/jats:styled-content>, close to 100\u00a0mg\/ml) or low (<jats:styled-content style=\"fixed-case\">LFM<\/jats:styled-content>, close to 30\u00a0mg\/ml) IgG concentration. At 12\u00a0hr of life, three treatments of second colostrum feeding were applied to the calves either fed high or low first colostrum: calves fed with low (<jats:styled-content style=\"fixed-case\">LOW<\/jats:styled-content>\u2014close to 30\u00a0mg\/ml) or high (<jats:styled-content style=\"fixed-case\">HIGH<\/jats:styled-content>\u2014close to 100\u00a0mg\/ml) IgG concentration; and colostrum enriched with lyophilized bovine colostrum with high IgG concentration (<jats:styled-content style=\"fixed-case\">ENRICHED<\/jats:styled-content>\u2014higher than 120\u00a0mg\/ml), resulting in six groups. Intestinal samples were collected after 24 and 72\u00a0hr of life. In the distal jejunum and ileum, <jats:styled-content style=\"fixed-case\">LOW<\/jats:styled-content> showed higher villus height than <jats:styled-content style=\"fixed-case\">ENRICHED<\/jats:styled-content> (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). In the distal jejunum, greater villus perimeter was observed in the <jats:styled-content style=\"fixed-case\">LOW<\/jats:styled-content> compared to <jats:styled-content style=\"fixed-case\">ENRICHED<\/jats:styled-content> at 24\u00a0hr (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). In ileum, <jats:styled-content style=\"fixed-case\">LFM<\/jats:styled-content> showed higher villus perimeter compared to <jats:styled-content style=\"fixed-case\">HFM<\/jats:styled-content> (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). <jats:styled-content style=\"fixed-case\">LOW<\/jats:styled-content> showed the highest villus height\u2010to\u2010crypt depth ratio in the medium and distal jejunum and ileum, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05. <jats:styled-content style=\"fixed-case\">ENRICHED<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HFM<\/jats:styled-content> showed decreased muscle layer thickness in the proximal and distal jejunum respectively (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). The results reveal that the high concentration of total solids, crude protein, IgG and <jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u2010I of colostrum with high quality worsened the absorptive area, but may have stimulated the activity of cell division in intestinal crypts. Considering the present results, bovine colostrum enriched with lyophilized bovine colostrum stimulates intestinal epithelium renewal of Holstein calves in the first days of life.<\/jats:p>","DOI":"10.1111\/jpn.12780","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T05:38:48Z","timestamp":1499665128000},"page":"514-524","source":"Crossref","is-referenced-by-count":8,"title":["Bovine colostrum enriched with lyophilized bovine colostrum stimulates intestinal epithelium renewal of Holstein calves in the first days of life"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3925-1128","authenticated-orcid":false,"given":"L.","family":"Kindlein","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine Veterinary Veterinary Faculty Rio Grande do Sul Federal University (UFRGS)  Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. B.","family":"Moretti","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Anatomy and Physiology Department of Animal Science Luiz de Queiroz College of Agriculture (ESALQ) University of S\u00e3o Paulo (USP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Pauletti","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Anatomy and Physiology Department of Animal Science Luiz de Queiroz College of Agriculture (ESALQ) University of S\u00e3o Paulo (USP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"Bagaldo","sequence":"additional","affiliation":[{"name":"Centre of Agricultural Environmental and Biological Sciences Federal University of Bahia Rec\u00f4ncavo (UFRB)  Cruz das Almas Bahia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. P. O.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Brazilian Agricultural Research Corporation (EMBRAPA) Ministry of Agriculture Livestock and Food Supply  Palmas Tocantins Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Machado\u2010Neto","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Anatomy and Physiology Department of Animal Science Luiz de Queiroz College of Agriculture (ESALQ) University of S\u00e3o Paulo (USP)  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0305-0491(99)00140-6","article-title":"Effect of turkey (Meleagridid gallopavo) breeder hen age and egg size on poult development. 2. 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