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Liver, breast muscle, duodenum, jejunum, and ileum were collected at day 10 (d10) and d26 to assay markers of oxidative stress, including total glutathione (TGSH), oxidized glutathione (GSSG), reduced glutathione (rGSH), protein carbonyls, thiobarbituric acid reactive substances (TBARS) and ferric reducing\/antioxidant power (FRAP). In breast muscle, TGSH and rGSH were greater in L\u2010Met and DL\u2010HMTBA groups than in the control group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). An interaction of treatment and age was observed for TGSH in ileum (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01) and jejunum (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01), for GSSG in jejunum (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and for rGSH in ileum (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.02). The ratios of rGSH to GSSG and GSSG to TGSH, which define oxidative status, were not affected by Met source. Protein carbonyls varied among groups in jejunum (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.05) and breast muscle (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), but were in the normal physiological range. No difference among treatment groups was observed for TBARS and FRAP in different tissues. Age effects were observed in all tissues for multiple oxidative stress markers. In conclusion, consuming different sources of supplementary Met did not alter the oxidative status in several tissues of broilers. Met + Cys deficiency did not compromise antioxidant capacity of chickens although growth was retarded.<\/jats:p>","DOI":"10.1111\/jpn.12946","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T10:46:41Z","timestamp":1530614801000},"page":"1274-1283","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Supplemental methionine sources have a neutral impact on oxidative status in broiler chickens"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5435-2640","authenticated-orcid":false,"given":"Shuai","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Animal and Poultry Sciences Virginia Tech  Blacksburg Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth R.","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Department of Animal and Poultry Sciences Virginia Tech  Blacksburg Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behnam","family":"Saremi","sequence":"additional","affiliation":[{"name":"Evonik Nutrition &amp; 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