{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:09:48Z","timestamp":1789924188161,"version":"4.0.1"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T00:00:00Z","timestamp":1559088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An experiment was conducted to investigate the supplementation of two commercially available multistrain probiotics as an alternative to antibiotics on growth performance, intestinal morphology, lipid oxidation and ileal microflora in broiler chickens. A total of 280\u2010day\u2010old ROSS 308 mixed\u2010sex broiler chickens with an average initial body weight of 42\u00a0\u00b1\u00a00.5\u00a0g were randomly divided into four treatments with five replicate cages of 14 birds each cage in a completely randomized design and fed with the following diets for 42\u00a0day: (a) control (CON) (antibiotic\u2010free diet), (b) antibiotic (ANT) (CON\u00a0+\u00a0Avilamycin 150\u00a0g\/ton feed), (c) probiotic A (CON\u00a0+\u00a0Protexin<jats:sup>\u00ae<\/jats:sup> 150\u00a0g\/ton feed) and (d) probiotic B (CON\u00a0+\u00a0Bio\u2010Poul<jats:sup>\u00ae<\/jats:sup> 200\u00a0g\/ton feed). The results showed the broilers fed the ANT diet had greater average daily gain than broilers fed the CON diet during day 1\u201314 (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). At day 42, two birds were randomly selected per replicate for evaluation intestinal morphology, lipid oxidation and ileal microflora. birds fed diet supplemented with probiotic A and probiotic B increased villus height and goblet cells numbers in the jejunum and villus height to crypt depth ratio and villus height in the ileum as compared to birds fed CON diet (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). The malondialdehyde value was reduced (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) in the ANT, probiotic B and probiotic A groups compared with the CON group. The <jats:italic>Lactobacillus<\/jats:italic> population was increased and <jats:italic>Clostridium<\/jats:italic> spp. population decreased in the ileum of broilers fed diets containing the probiotic B and probiotic A compared with those fed CON diet (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). The results from this study indicate that the probiotic A (Protexin<jats:sup>\u00ae<\/jats:sup>) and probiotic B (Bio\u2010Poul<jats:sup>\u00ae<\/jats:sup>) used in this trial may serve as alternatives to ANT.<\/jats:p>","DOI":"10.1111\/jpn.13124","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T13:11:31Z","timestamp":1559135491000},"page":"1399-1407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Evaluating two multistrain probiotics on growth performance, intestinal morphology, lipid oxidation and ileal microflora in chickens"],"prefix":"10.1111","volume":"103","author":[{"given":"Seyed Amin","family":"Kazemi","sequence":"first","affiliation":[{"name":"Department of Poultry Science, Faculty of Agriculture Tarbiat Modares University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7445-3139","authenticated-orcid":false,"given":"Hamed","family":"Ahmadi","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, Faculty of Agriculture Tarbiat Modares University Tehran Iran"},{"name":"Bioscience and Agriculture Modeling Research Unit, Department of Poultry Science Tarbiat Modares University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8141-4904","authenticated-orcid":false,"given":"Mohammad A.","family":"Karimi Torshizi","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, Faculty of Agriculture Tarbiat Modares University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/09712119.2016.1219665"},{"key":"e_1_2_5_3_1","first-page":"199","article-title":"Mannan oligosaccharide and organic acids on performance and intestinal morphometric characteristics of broiler chickens","volume":"14","author":"Adil S.","year":"2001","journal-title":"International Journal of Poultry Science"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2013-03718"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.1999.tb15870.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-4573.2005.00023.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox2040326"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.3214"},{"key":"e_1_2_5_9_1","first-page":"152","article-title":"Effect of dietary supplementation of probiotic and prebiotic on growth indices and serum biochemical parameters of broiler chickens","volume":"5","author":"Ashayerizadeh A.","year":"2011","journal-title":"Journal of Cell and Animal Biology"},{"key":"e_1_2_5_10_1","first-page":"78","article-title":"Effects of dietary inclusion of protexin (probiotic) on hatchability of Japanese quails","volume":"83","author":"Ayasan T.","year":"2013","journal-title":"Indian Journal Animal Science"},{"key":"e_1_2_5_11_1","first-page":"237","article-title":"Effects of incorporating an antibiotic \"Avilamycin\" and a probiotic \"Activis\" in broiler diets","volume":"55","author":"Ayed M. 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