{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:38:37Z","timestamp":1789094317916,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T00:00:00Z","timestamp":1566864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 7\u2010year\u2010old mixed breed spayed bitch (body weight: 10.6\u00a0kg) was presented with a history of intermittent episodes of seizures and untreated limb fracture. Appetite loss, nervousness, lateral recumbency, fasciculations, ataxia and poor nutritional condition were found. Venous blood gas analysis highlighted normal acid\u2010base balance and severe low ionized calcium (0.58\u00a0mEq\/L [range 1.13\u20131.32\u00a0mEq\/L]). Marked total hypocalcaemia (6.4\u00a0mg\/dL [range 8\u201310] or 1.6\u00a0mM [range: 2\u20132.5]) associated with hyperphosphoraemia (9.3\u00a0mg\/dl [range 3.5\u20136.5\u00a0mg\/dl]) displayed inverted ratio between minerals. <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> showed sinus arrhythmias. Circulating levels of Mg and Cu were within physiological range (1.97\u00a0mg\/dl and 128\u00a0\u03bcg\/dl respectively) and effects from interactions were excluded. Oral administration of calcitriol at 40\u00a0ng\/kg\/day led to clinical improvement within 48\u00a0hours, but circulating <jats:styled-content style=\"fixed-case\">iC<\/jats:styled-content>a levels were still below the lower limit of the reference range. Baseline levels of circulating parathormone (<jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content>) were 3\u00a0pg\/ml, along with normal values of circulating vitamin D. Primary hypoparathyroidism was diagnosed as a chronic underlying condition triggered by pelvic fracture.<\/jats:p>","DOI":"10.1111\/jpn.13187","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T02:09:55Z","timestamp":1566958195000},"page":"119-123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pelvic fracture triggering symptoms of an underlying primary hypoparathyroidism in an adult spayed bitch: A case report"],"prefix":"10.1111","volume":"105","author":[{"given":"Isabella","family":"Ballocco","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8863-9834","authenticated-orcid":false,"given":"Maria Grazia","family":"Cappai","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Antonietta","family":"Evangelisti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Carta","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Pirari","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Lucia Gabriella","family":"Manunta","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Veterinary Teaching Hospital (VTH) University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,27]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2003.08.004"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317\u201034\u20106\u2010503"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939\u20101676.1988.tb01971.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.4081\/ijas.2013.e29"},{"key":"e_1_2_4_6_1","first-page":"340","volume-title":"Kirk's current veterinary therapy XIII small animal practice","author":"Chew D. 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