{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T08:25:38Z","timestamp":1778919938517,"version":"3.51.4"},"reference-count":59,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["TD2019C001"],"award-info":[{"award-number":["TD2019C001"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The increase in feed costs has led feeder to replace protein source. Blood meal can be used in piglet diets instead of fish meal (FM). The objective of this study was to investigate the effect of fermented blood cells (FBCs) on the growth performance and intestinal health of weaned piglets. One hundred eighty 28\u2010day\u2010old piglets were assigned and were divided into 4 groups (9\u00a0L per groups and 5 pigs per litters) randomly. The piglets were fed one of four experimental diets, fish meal, blood cells (BCs), liquid\u2010state fermented blood cells (LFBCs) or solid\u2010state fermented blood cells (SFBCs) respectively. The dietary with LFBCs and SFBCs increased the average daily gain and feed intake (ADFI) and average daily gain (ADG) (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). In duodenum, LFBC group increased the villous height (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). The SFBC and LFBC group significantly increased the villous height (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) in the jejunum. Fermented blood cells exhibit a positive regulatory function on the intestinal tract and modulate intestinal microflora. Compared with the fish meal group, the CAT, GSH\u2010PX and SOD activity, and MDA level was no significant differences in jejunum and plasma of weaned piglets (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05). LFBCs and SFBCs significantly increased the bifidobacteria and lactobacillus number in the caecum (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). Dietary LFBCs increased the expression of ZO\u20101 mRNA in the jejunal of weaned piglets (<jats:italic>p\u00a0&lt;\u00a0<\/jats:italic>.05). In conclusion, dietary with fermented blood cells in weaned piglets had improved growth\u00a0performance and intestinal health of weaned piglets.<\/jats:p>","DOI":"10.1111\/jpn.13194","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T14:33:12Z","timestamp":1567607592000},"page":"1875-1884","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of fermented blood cells on growth performance and intestinal characteristics of weaned piglets"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5424-2772","authenticated-orcid":false,"given":"Boru","family":"Zhang","sequence":"first","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingwei","family":"Meng","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chongpeng","family":"Bi","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-7509","authenticated-orcid":false,"given":"Anshan","family":"Shan","sequence":"additional","affiliation":[{"name":"Institute of Animal Nutrition Northeast Agricultural University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2741\/3413"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0044-8486(86)90168-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2011.08.039"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.70.6.3575-3581.2004"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2004.06.008"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2527\/2003.8182019x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2006.05.005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.11.055"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2016.02.003"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-445X(00)00145-4"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.280.3.G315"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(99)00354-3"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(02)00182-4"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2015.02.024"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2527\/1994.7282090x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2016.04.008"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731107661850"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1300\/J028v05n03_06"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.21273\/HORTTECH.17.4.431"},{"issue":"4","key":"e_1_2_6_21_1","first-page":"409","article-title":"Evaluation of soybean meal\u2010red blood cell coextruded feed ingredient in diets fed to rainbow trout Oncorhynchus mykiss","volume":"32","author":"George L. 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