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Twenty multiparous sows, with a history of hyperprolificacy (more than 14 piglets per litter), were used. A completely randomized experimental design was used, consisting of two treatments: feed supplemented or not with 1% L\u2010arginine from days 85 to 115 of gestation. The experimental unit consisted of the sow and its respective litter, using 10 replicates per treatment. The sows were distributed into the treatments based on body condition and parity. Supplementation with L\u2010arginine reduced the within\u2010litter standard deviation and the within\u2010litter coefficient of variation of piglet weight at 24\u00a0hr by 54\u00a0g and 4.14 percentage points respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.029; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.035). Supplementation with 1.0% L\u2010arginine decreased the percentages of piglets weighing less than 800\u00a0g by 5.60 and 5.08 points at birth and at 24\u00a0hr of life respectively. Piglets from sows supplemented with L\u2010arginine had higher (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.088) average rectal temperatures at birth and lower (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.030) rectal temperature at 24\u00a0hr of life in comparison with control piglets. No significant differences in placental weight or estimated colostrum production and intake were observed in the first 24\u00a0hr of life. At 24\u00a0hr of life, piglets weighing less than 1,000\u00a0g and from supplemented sows had lower (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.048) surface\/mass ratios and higher body mass index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.070). Piglets from supplemented sows and who weighed 1601 to 1,800\u00a0g had lower body mass index and ponderal index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.003). Supplementation with L\u2010arginine during the final third of gestation reduces the incidence of unviable piglets (&lt;800\u00a0g) and improved litter uniformity and piglets\u2019 body conformation within the first 24\u00a0hr of life.<\/jats:p>","DOI":"10.1111\/jpn.13305","type":"journal-article","created":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T12:24:16Z","timestamp":1580214256000},"page":"645-656","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["L\u2010arginine supplementation during the final third of gestation improves litter uniformity and physical characteristics of neonatal piglet thermoregulation"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-5750","authenticated-orcid":false,"given":"Rennan Herculano Rufino","family":"Moreira","sequence":"first","affiliation":[{"name":"Department of Animal Science Universidade Federal Rural do Semi\u2010\u00c1rido Mossor\u00f3 Rio Grande do Norte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8542-3069","authenticated-orcid":false,"given":"Melissa Fab\u00edola dos Santos Alves","family":"Mendes","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3350-3670","authenticated-orcid":false,"given":"Jorge Yair P\u00e9rez","family":"Palencia","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences South Dakota State University Brookings SD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Alves Gomes","family":"Lemes","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andressa Rodrigues","family":"Roque","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Kutschenko","sequence":"additional","affiliation":[{"name":"Ajinomoto do Brasil Ind. e Com. de Alimentos S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-9306","authenticated-orcid":false,"given":"Rony Ant\u00f4nio","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5272-3233","authenticated-orcid":false,"given":"M\u00e1rvio Lob\u00e3o Teixeira","family":"de Abreu","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2013-6824"},{"key":"e_1_2_9_3_1","first-page":"151","article-title":"Influence of dietary L\u2010arginine supplementation to sows during late gestation on sow and litter performance during lactation","volume":"597","author":"Bass B. 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