{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:41:21Z","timestamp":1778085681411,"version":"3.51.4"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T00:00:00Z","timestamp":1583107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to determine the effect of sodium butyrate (SB) on reproductive tract development and histomorphometric analysis of testes in neonatal kids, as well as on their growth, antioxidant status and some blood metabolites. Thirty\u2010six neonatal Zaraibi kids were divided immediately after 4\u20135\u00a0days from birth into three equal groups (12 kids\/ each). The first group (G1) received milk replacer (MR) at a rate of 10% of the body weight until the weaning. The second group (G2) received 9.7% MR supplemented with 0.3% SB. The third group (G3) received whole milk and served as a control. The results revealed that there was significant (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001) increase in total and daily gain between the G2 and G1 groups, whereas there was no significant change between G2 and G3 groups. Body condition score was slightly increased (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05) in G2 compared with G1. Serum total protein and cholesterol levels were significantly decreased in treated groups compared with the G3 group, on reverse globulin and glucose levels had no significant changes. Also, T3 and testosterone concentrations were significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001 &amp; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) higher in G3 and G2 than G1. Antioxidant status was enhanced through decreasing the oxidative marker and increasing antioxidant enzymes activity in G2. Testis parameters in G3 and G2 kids had the highest values, compared with G1. G1 and G2 had thin basement membrane of seminiferous tubules with few Leydig cells and pyknotic germinal epithelium, while G3 showed thick basement membrane, mild wide interstitial spaces with many Leydig cells. The tubular diameter was also significantly larger in the G3 and G2. It could be concluded that MR supplemented with SB can be used as alternative whole milk in suckling goat kids for maintaining reproductive tract and kids' performance through improving the antioxidant status.<\/jats:p>","DOI":"10.1111\/jpn.13334","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T09:44:42Z","timestamp":1583142282000},"page":"812-822","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Reproductive tract development and histomorphometric analysis of testes in neonatal Zaraibi kids raised on milk replacer supplemented with sodium butyrate"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9424-2523","authenticated-orcid":false,"given":"Mahmoud Yassin","family":"Mohamed","sequence":"first","affiliation":[{"name":"Animal Physiology Division, Sheep and Goat Research Department Animal Production Research Institute (APRI) Agricultural Research Center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma E.","family":"Saba","sequence":"additional","affiliation":[{"name":"Animal Husbandry Division Sheep and Goat Research Department Animal Production Research Institute (APRI) Agricultural Research Center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelhameed A. A. I.","family":"Gomaa","sequence":"additional","affiliation":[{"name":"Animal Husbandry Division Sheep and Goat Research Department Animal Production Research Institute (APRI) Agricultural Research Center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed L. I.","family":"Desoky","sequence":"additional","affiliation":[{"name":"Animal Husbandry Division Sheep and Goat Research Department Animal Production Research Institute (APRI) Agricultural Research Center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman A.","family":"Almwafy","sequence":"additional","affiliation":[{"name":"Toxicology Division Veterinary Services Department Animal Production Research Institute (APRI) Agricultural Research center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omnia M.","family":"AbdEl\u2010Salam","sequence":"additional","affiliation":[{"name":"Animal Physiology Division, Sheep and Goat Research Department Animal Production Research Institute (APRI) Agricultural Research Center (ARC) Giza Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eid M. 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