{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:08:47Z","timestamp":1759010927716,"version":"3.40.5"},"reference-count":47,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This experiment was conducted to investigate the effects of dietary supplementation with coated granules (CG) on performance, <jats:italic>in vitro<\/jats:italic> digestibility and the gastrointestinal functionality in laying hens. A total of 40 Hisex Brown laying hens (36\u00a0weeks of age) were randomly divided into five equal groups; one served as a control and the other four were actual experimental groups supplemented with 0.75, 1.5, 3 or 6\u00a0g CG per day. All the hens were fed restrictively with target feed intake of 100\u00a0g basal diet\/hen per day. There were no differences in egg production or egg weight among the groups, but feed conversion ratio was significantly improved (linearly, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05) with the dose level of CG in diet. Dietary CG increased the jejunal weight (linear and quadratic terms, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05) but decreased the ileal weight (linearly, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). There was mostly statistical interaction between dietary CG and specific activity of intestinal digestive enzymes with similar patterns for dietary CG treatments (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). A positive linear correlation was observed with <jats:italic>in vitro<\/jats:italic> protein digestibility by using the crude enzyme extract from dietary CG supplementation. Dietary CG decreased the caecal <jats:italic>Escherichia coli<\/jats:italic> population while the <jats:italic>Lactobacillus<\/jats:italic> spp.: <jats:italic>E<\/jats:italic>.\u00a0<jats:italic>coli<\/jats:italic> ratio increased (quadratic fit, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). CG supplementation, on the other hand, significantly altered intestinal morphology by increasing the height of duodenal and ileal villi (linearly, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). Also, duodenal antioxidant capacity observed via remaining reducing power improved linearly (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05). This suggests that CG, unlike garlic oils without encapsulation, may be a good candidate for feed supplementation in commercial egg production. It could be included up to 6\u00a0g CG per day without any adverse effects on performance, which may relate to improving nutrient digestibility and better utilization of limited feed intake when using a low amount of diet or other observations in this study.<\/jats:p>","DOI":"10.1111\/jpn.13554","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T15:48:27Z","timestamp":1619538507000},"page":"118-131","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of dietary coated granules containing garlic oil diallyl disulphide and diallyl trisulphide on performance, <i>in vitro<\/i> digestibility and gastrointestinal functionality in laying hens"],"prefix":"10.1111","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4916-0833","authenticated-orcid":false,"given":"Prawit","family":"Rodjan","sequence":"first","affiliation":[{"name":"Program in Tropical Agricultural Resource Management Faculty of Natural Resources Prince of Songkla University  Hat Yai, Songkhla Thailand"},{"name":"Center of Excellence in Agricultural and Natural Research Biotechnology Phase 3 Faculty of Natural Resources Prince of Songkla University  Hat Yai, Songkhla Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sutha","family":"Wattanasit","sequence":"additional","affiliation":[{"name":"Center of Excellence in Agricultural and Natural Research Biotechnology Phase 3 Faculty of Natural Resources Prince of Songkla University  Hat Yai, Songkhla Thailand"},{"name":"Department of Animal Science Faculty of Natural Resources Prince of Songkla University  Hat Yai, Songkhla Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3534-831X","authenticated-orcid":false,"given":"Karun","family":"Thongprajukaew","sequence":"additional","affiliation":[{"name":"Division of Health and Applied Science Faculty of Science Prince of Songkla University  Hat Yai, Songkhla Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damrongsak","family":"Faroongsarng","sequence":"additional","affiliation":[{"name":"Drug Delivery System Excellent Center Department of Pharmaceutical Technology Faculty of Pharmaceutical Science Prince of Songkla University  Hat Yai, Songkhla Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2010.12.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2141\/jpsa.43.378"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2003.12.008"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2008-00244"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0396.2010.00999.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1996.0292"},{"volume-title":"Biochemistry","year":"2002","author":"Berg J. 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