{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:11:45Z","timestamp":1779916305137,"version":"3.53.1"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T00:00:00Z","timestamp":1654819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972589"],"award-info":[{"award-number":["31972589"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Buffalo milk contains more polyunsaturated fatty acids than bovine milk. However, it is not clear about the effects of buffalo milk and bovine milk on lipid metabolism. In this study, a mouse model was used to explore the effects of buffalo milk and bovine milk on lipid metabolism in mice. The experiment was divided into three groups: a control group on a normal diet; a bovine milk group infused with bovine milk; a buffalo milk group infused with buffalo milk. We fed three groups of mice (<jats:italic>n<\/jats:italic>\u2009=\u20096) for 6 weeks. These results showed that bovine milk and buffalo milk had no effect on body weight gain. Bovine milk increased the content of ApoA1, ApoB\u00a0and glucose in serum, compared with the control group, but buffalo milk has no profound change in serum ApoB. Remarkably, buffalo milk decreased the content of total cholesterol (TC) and triglyceride (TG) in the liver lipid profile, and also downregulated the expression of the carnitine palmitoyltransferase 2 (Cpt2) gene involved in the fatty acid oxidation in the liver. This study also found that bovine milk and buffalo milk did not cause the expression of pro\u2010inflammatory factors in serum and colon tissues. This experiment proved that buffalo milk has beneficial effects on the regulation of lipid metabolism, and also does not affect the normal growth and pro\u2010inflammatory response of the colon in mice. It provides a theoretical basis for future in\u2010depth research on the special functions of buffalo milk and the development of buffalo milk functional foods.<\/jats:p>","DOI":"10.1111\/jpn.13740","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T09:01:13Z","timestamp":1654851673000},"page":"428-434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of bovine milk and buffalo milk on lipid metabolism in mice"],"prefix":"10.1111","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7171-1131","authenticated-orcid":false,"given":"Kang","family":"Yan","sequence":"first","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoYu","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MaoCheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZiXuan","family":"Hu","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TianYu","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Zhan","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GuoQi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Institute of Animal Culture Collection and Application, College of Animal Science and Technology Yangzhou University  Yangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,10]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"62","article-title":"Composition and physico\u2010chemical characteristics of buffalo milk with particular emphasis on lipids, proteins, minerals, enzymes and vitamins","volume":"23","author":"Ahmad S.","year":"2013","journal-title":"J Anim Plant Sci"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"Triglyceride metabolism in the liver","volume":"8","author":"Alves\u2010Bezerra M.","year":"2017","journal-title":"Comprehensive Physiology"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.6.1454"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2004.06.004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20466"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.11.6164"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/db07-1403"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(18)30324-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani10020327"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH13-02-0178"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14234-1"},{"key":"e_1_2_8_13_1","first-page":"141","volume-title":"Food microbiology: Fundamentals and frontiers","author":"Frank J. 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