{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:15:45Z","timestamp":1776705345408,"version":"3.51.2"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T00:00:00Z","timestamp":1659830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to assess the effects of different spray\u2010dried plasma (SDP) feeding programmes to pigs on performance, intestinal histomorphology and faecal bacterial shedding after an <jats:italic>Escherichia coli<\/jats:italic> K88 challenge. A total of 96 piglets (5.77\u2009\u00b1\u20090.01\u2009kg) were weaned at 21 days of age (Day 0) and challenged with 3\u2009ml of 1\u2009\u00d7\u200910<jats:sup>10<\/jats:sup>\u2009CFU of <jats:italic>E. coli<\/jats:italic> K88 in total 3.0\u2009\u00d7\u200910<jats:sup>10<\/jats:sup>\u2009CFU\/animal on Days 0, 2 and 4. Pigs were fed nursery diets containing 0.0%, 3.0%, 6.0% or 9.0% SDP from weaning to 35 days of age; 0.0%, 1.5%, 3.0% or 4.5% SDP from 36 to 49 days; and the same control diet (without SDP), for the last 10 days of the experiment (50\u221259 days of age). Performance was measured from 35 to 59 days of age and faecal bacterial shedding and intestinal histomorphometry were evaluated at Days 28 and 49 of age\u00a0respectively. From 21 to 35 days of age, there was a linear effect for body weight (BW) and average daily gain (ADG), a trend of linear effect for average daily feed intake (ADFI) and a quadratic effect for feed:gain ratio (FG). From 21 to 49 days, the 9.0:4.5% and 6.0:3.0% SDP feeding programmes improved BW, ADG and FG when compared to the other treatments. At 59 days of age, BW and ADG were increased by the two highest SDP feeding programmes. The 9.0:4.5% SDP feeding programme increased ADFI from 21 to 59 days of age, with 6.0:3.0% being intermediate and the other two treatments being lowest. The CFU counts of <jats:italic>E. coli<\/jats:italic>\/g of faeces decreased linearly with increasing addition of SDP. These results indicate that an extended inclusion of increased SDP levels in post\u2010weaning diets can improve growth potential and decrease bacterial shedding induced by <jats:italic>E.\u00a0coli<\/jats:italic> K88.<\/jats:p>","DOI":"10.1111\/jpn.13761","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T06:53:45Z","timestamp":1659941625000},"page":"581-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A dietary spray\u2010dried plasma feeding programme improves growth performance and reduces faecal bacterial shedding of nursery pigs challenged with enterotoxigenic <i>Escherichia coli<\/i> K88"],"prefix":"10.1111","volume":"107","author":[{"given":"Pedro G.","family":"Castelo","sequence":"first","affiliation":[{"name":"Department of Animal Science Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas A.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"College of Agriculture and Bioresources University of Saskatchewan  Saskatoon Canada"},{"name":"Prairie Swine Centre, Inc.  Saskatoon Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele de P.","family":"Gabardo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinics and Surgery Federal University of Minas Gerais  Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto M.\u00a0Carvalho","family":"Guedes","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine and Animal Health University of S\u00e3o Paulo  Butant\u00e3 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea M.","family":"Moreno","sequence":"additional","affiliation":[{"name":"Federal Institute of Minas Gerais  Bambu\u00ed Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda M.","family":"Coura","sequence":"additional","affiliation":[{"name":"Federal Institute of Minas Gerais  Bambu\u00ed Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Bryan","family":"Heinemann","sequence":"additional","affiliation":[{"name":"Federal Institute of Minas Gerais  Bambu\u00ed Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno O.","family":"Rosa","sequence":"additional","affiliation":[{"name":"Department of Animal Science Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana P.\u00a0L.","family":"Brustolini","sequence":"additional","affiliation":[{"name":"Department of Animal Science Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8882-3180","authenticated-orcid":false,"given":"Itallo C.\u00a0S.","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Department of Animal Science Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalton de\u00a0O.","family":"Fontes","sequence":"additional","affiliation":[{"name":"Department of Animal Science Federal University of Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,7]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"39","article-title":"An investigation of the presence of Escherichia coli O149:K91:F4 on pig farms in southern Ontario and the use of antimicrobials and risk factors associated with the presence of this serogroup","volume":"49","author":"Amezcua R.","year":"2008","journal-title":"Canadian Veterinary Journal"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1071\/AN141021"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2527\/2004.8261764x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451400422X"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skx062"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2527\/1995.7392532x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2006.12.011"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S175173110900398X"},{"issue":"3871","key":"e_1_2_7_10_1","first-page":"K88","article-title":"Chito\u2010oligosaccharide reduces diarrhea incidence and attenuates the immune response of weaned pigs challenged with Escherichia coli","volume":"88","author":"Liu P.","year":"2010","journal-title":"Journal of Animal Science"},{"key":"e_1_2_7_11_1","volume-title":"Clinical veterinary microbiology E\u2010book","author":"Markey B.","year":"2013"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0059838"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2527\/2003.8171781x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.136796"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i33.11713"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2527\/2005.83122876x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40813-016-0021-6"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2015.05.006"},{"key":"e_1_2_7_19_1","first-page":"186","article-title":"Tabelas brasileiras para aves e su\u00ednos","volume":"2","author":"Rostagno H. 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