{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T09:13:42Z","timestamp":1770714822320,"version":"3.49.0"},"reference-count":61,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Moringa oleifera<\/jats:italic> (MO), a cultivated species of the Moringa, is known for its high concentration of essential nutrients that promote growth. To assess its impact on rabbits' gut morphometric, behavioural, and physiological parameters, a study was conducted using sixty growing male white New Zealand rabbits at 40 days old. The rabbits were divided into four groups and supplemented with dried MO leaves at varying levels (0%, 0.5%, 1% and 2% of body weight) for four weeks. The results revealed significant increases in organ weights, such as liver and intestinal length, and the height of intestinal villi and crypt depth in the large intestine. The muscular layer's and submucosa's thickness also increased in different parts of the intestine in rabbits fed with MO compared to the control group. No significant effect was observed on the caecum mucosa depth. Interestingly, no significant differences were found in body weight or weight gain between the Moringa supplementation groups and the control group. However, rabbits offered 0%, 0.5% and 1% MO spent more time feeding and resting than those given 2% MO. The grooming and sniffing percentage remained unaffected by Moringa supplementation. Regarding blood parameters, rabbits that received MO leaves in their diet showed improvements in red blood cell count, haemoglobin levels, packed cell volume, white blood cell count, neutrophil count, total protein, globulin, and A\/G ratio. Moreover, there was a significant decrease in malondialdehyde levels and an increase in glutathione and high\u2010density lipoprotein levels, indicating an antioxidative effect. Overall, the study concluded that MO leaves supplementation in the rabbit diet positively influenced the rabbits' health by modulating the immune system, improving histological aspects of the intestine, liver, and spleen, and enhancing physiological parameters through its antioxidative properties.<\/jats:p>","DOI":"10.1111\/jpn.13967","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T11:55:42Z","timestamp":1713354942000},"page":"1214-1230","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of dietary <i>Moringa oleifera<\/i> leaf supplementation on gut morphometry, behaviour and physiological parameters in growing male rabbits"],"prefix":"10.1111","volume":"108","author":[{"given":"Seham S.","family":"Hadad","sequence":"first","affiliation":[{"name":"Department of Anatomy and Embryology, Faculty of Veterinary Medicine University of Sadat City Sadat City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enas K.","family":"Aziz","sequence":"additional","affiliation":[{"name":"Department of Husbandry and Animal Wealth Development, Animal Behaviour and Management, Faculty of Veterinary Medicine University of Sadat City Sadat City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel Hassan","family":"Saad","sequence":"additional","affiliation":[{"name":"Nutrition and Clinical Nutrition Department, Faculty of Veterinary Medicine Matrouh University Matrouh Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanem","family":"El\u2010Gendy","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Veterinary Medicine University of Sadat City Sadat City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazema","family":"Abdel\u2010Megeid","sequence":"additional","affiliation":[{"name":"Department of Cytology and Histology, Faculty of Veterinary Medicine University of Sadat City Sadat City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimaa R.","family":"Masoud","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Medicine University of Sadat City Sadat City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2722-2466","authenticated-orcid":false,"given":"Mustafa","family":"Shukry","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Medicine Kafrelsheikh University Kafrelsheikh Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3247-5898","authenticated-orcid":false,"given":"Ayman A.","family":"Swelum","sequence":"additional","affiliation":[{"name":"Department of Animal Production, College of Food and Agriculture Sciences King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muath Q.","family":"Al\u2010Ghadi","sequence":"additional","affiliation":[{"name":"Department of Zoology, College of Sciences King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad R.","family":"Alhimaidi","sequence":"additional","affiliation":[{"name":"Department of Zoology, College of Sciences King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Tellez\u2010Isaias","sequence":"additional","affiliation":[{"name":"Department of Poultry Science University of Arkansas Fayetteville Arkansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2831-8534","authenticated-orcid":false,"given":"Mohamed E.","family":"Abd El\u2010Hack","sequence":"additional","affiliation":[{"name":"Poultry Department, Faculty of Agriculture Zagazig University Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed M. 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