{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:26:07Z","timestamp":1740126367210,"version":"3.37.3"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In an experiment with four treatments and five replicates, the effects of adding monosodium glutamate (MSG) to the diet in late phase of egg production was studied on performance, and lipid metabolism in laying hens. Dietary treatments included the control basal diet without MSG and the other treatments adding 0.4%, 0.8% and 1.2% MSG in the control diet respectively. The effect of supplementation of MSG on egg weight, egg production, feed conversion ratio and egg mass was insignificant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Adding MSG to the diet significantly increased feed intake and blood polyunsaturated fatty acids concentration (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Intake of 0.8% and 1.2% MSG in the diet up regulated the mRNA expression of acetyl\u2010coenzyme A carboxylase, fatty acid synthase\u00a0and lipoprotein lipase in the abdominal and liver tissues in comparison to the control group. Blood very low\u2010density lipoprotein\u2010cholesterol, triglycerides\u00a0and cholesterol concentration were increased in treatment fed with a diet containing 0.8% MSG compared to the control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The effect of MSG on total egg yolk cholesterol concentration was not significant. In conclusion, the results of the present experiment indicated that adding MSG increased feed intake and blood polyunsaturated fatty acid concentration.<\/jats:p>","DOI":"10.1111\/jpn.14003","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T07:14:56Z","timestamp":1718176496000},"page":"1578-1587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of monosodium glutamate supplementation in diet on fatty acid profiles, genes expression related to lipid metabolism and egg yolk cholesterol in late phase of production in laying hens"],"prefix":"10.1111","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1880-343X","authenticated-orcid":false,"given":"Mohammad","family":"Kazemifard","sequence":"first","affiliation":[{"name":"Department of Animal Science Sari Agricultural Sciences and Natural Resources University Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansour","family":"Rezaei","sequence":"additional","affiliation":[{"name":"Department of Animal Science Sari Agricultural Sciences and Natural Resources University Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Asghar","family":"Kardel","sequence":"additional","affiliation":[{"name":"Department of Animal Science Sari Agricultural Sciences and Natural Resources University Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zarbakht Ansari","family":"Pirsaraei","sequence":"additional","affiliation":[{"name":"Department of Animal Science Sari Agricultural Sciences and Natural Resources University Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0773-3966","authenticated-orcid":false,"given":"Essa","family":"Dirandeh","sequence":"additional","affiliation":[{"name":"Department of Animal Science Sari Agricultural Sciences and Natural Resources University Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijps.2008.215.222"},{"key":"e_1_2_9_3_1","first-page":"3260","article-title":"Effect of food additives (monosodium glutamate and sodium nitrite) on some biochemical parameters in albino rats","volume":"3","author":"Abdel\u2010Reheim E. S.","year":"2014","journal-title":"International Journal of bioassays"},{"key":"e_1_2_9_4_1","first-page":"5","article-title":"Comparative evaluation of cholesterol content and storage quality of chicken and quail eggs","volume":"4","author":"Adeniyi P. O.","year":"2016","journal-title":"World Journal Nutrition Health"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7095372"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.5455\/ajvs.197829"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.27462s"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-012-1280-4"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.27462y"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451000588X"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2004.10.013"},{"key":"e_1_2_9_12_1","first-page":"653","article-title":"Effects of high monosodium glutamate on some serum markers of lipid status in male Wistar rats","volume":"2","author":"Egbuonu A. C. C.","year":"2011","journal-title":"Journal of Medicine and Medical Sciences"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)64849-5"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/18.6.499"},{"key":"e_1_2_9_15_1","first-page":"285\u2013291","article-title":"Probiotics as an alternative approach to antibiotics for safe poultry meat production. Pakistan","volume":"42","author":"Gul S. T.","year":"2022","journal-title":"Veterinary Journal"},{"key":"e_1_2_9_16_1","unstructured":"He W.(2019).Utilization of energy substrates by chicken and pig enterocytes(Doctoral dissertation)."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joad.2016.08.007"},{"key":"e_1_2_9_18_1","first-page":"165","article-title":"Response of broiler chicks to dietary monosodium glutamate","volume":"29","author":"Khadija A.","year":"2009","journal-title":"Pakistan Veterinary Journal"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1471-4892(01)00101-1"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2011.06.012"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2015.06.023"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.29261\/pakvetj\/2023.103"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac60235a044"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-013-9576-8"},{"key":"e_1_2_9_26_1","first-page":"375","article-title":"Relation between abdominal fat and serum cholesterol, triglycerides, and lipoprotein concentrations in chicken breeds","volume":"31","author":"Musa H. H.","year":"2007","journal-title":"Turkish Journal of Veterinary & Animal Sciences"},{"key":"e_1_2_9_27_1","first-page":"1","article-title":"Quality parameters of eggs from chickens reared in deep litter system with or without access to grass or legume pasture","volume":"26","author":"Oke O. E.","year":"2014","journal-title":"Livestock Research for Rural Development"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.34233\/jpr.813355"},{"key":"e_1_2_9_29_1","first-page":"341","article-title":"Growth performance, blood indices and hormonal responses of broiler chickens fed monosodium glutamate. Iranian","volume":"12","author":"Olarotimi O. J.","year":"2022","journal-title":"Journal of Applied Animal Science"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.36782\/apjsafe.v9i2.104"},{"key":"e_1_2_9_31_1","first-page":"747\u2013757","article-title":"Ideal management of cholesterol level and prevention of coronary artery disease in women","volume":"10","author":"Pandit D. M.","year":"2023","journal-title":"International Journal of Research and Analytical Reviews"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-012-1420-x"},{"volume-title":"SAS User's Guide. Release 8.2","year":"2001","author":"SAS Institute","key":"e_1_2_9_33_1"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-8478cr20210540"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/09751270.2011.11885164"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0163-7827(02)00067-x"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0031-9384(00)00350-4"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.120.017066"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.29219\/fnr.v63.1444"},{"key":"e_1_2_9_40_1","first-page":"186","article-title":"Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats","volume":"47","author":"Thomas M.","year":"2009","journal-title":"Indian Journal of Experimental Biology"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejhm.2006.17916"},{"key":"e_1_2_9_42_1","first-page":"1","article-title":"Dietary guidelines for Americans","author":"You A.","year":"2015","journal-title":"US Department of Health and Human Services and US Department of Agriculture"},{"key":"e_1_2_9_43_1","unstructured":"Zealand F. S. A. N.(2003).Monosodium glutamate a safety assessment(Technical Report Series No. 20)."},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1039\/c6fo01329e"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00359-009-0446-3"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2018.12.050"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.5555\/uri:pii:0022214353901255"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/79.3.402"}],"container-title":["Journal of Animal Physiology and Animal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jpn.14003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T09:36:43Z","timestamp":1735637803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jpn.14003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,12]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/jpn.14003"],"URL":"https:\/\/doi.org\/10.1111\/jpn.14003","archive":["Portico"],"relation":{},"ISSN":["0931-2439","1439-0396"],"issn-type":[{"type":"print","value":"0931-2439"},{"type":"electronic","value":"1439-0396"}],"subject":[],"published":{"date-parts":[[2024,6,12]]},"assertion":[{"value":"2024-01-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}